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Tdark
CCDC77
Coiled-coil domain-containing protein 77

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000239830
  • ENSP00000239830
  • ENSG00000120647
  • ENST00000412006
  • ENSP00000412925
  • ENST00000422000
  • ENSP00000391870
  • ENST00000540180
  • ENSP00000440554
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.82
transcription factor
0.8
histone modification site profile
0.72
cell line
0.57
cellular component
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
IKZF5
Tbio
Family:  TF
Novelty:  0.36596327
p_int:  0.999998949
p_ni:  0.000001043
p_wrong:  8e-9
Data Source:  BioPlex
PRDM5
Tbio
Family:  TF; Epigenetic
Novelty:  0.01689997
p_int:  0.999997082
p_ni:  0.000002732
p_wrong:  1.86e-7
Score:  0.183
Data Source:  BioPlex,STRINGDB
CCDC136
Tbio
Novelty:  0.09279967
p_int:  0.999995966
p_ni:  0.000002411
p_wrong:  0.000001623
Score:  0.188
Data Source:  BioPlex,STRINGDB
LTBR
Tbio
Novelty:  0.003823
p_int:  0.999993267
p_ni:  0.000006728
p_wrong:  5e-9
Score:  0.181
Data Source:  BioPlex,STRINGDB
SYT12
Tbio
Novelty:  0.03410873
p_int:  0.998289258
p_ni:  0.000202763
p_wrong:  0.001507979
Score:  0.188
Data Source:  BioPlex,STRINGDB
AURKAIP1
Tchem
Family:  Enzyme
Novelty:  0.19241693
Score:  0.727
Data Source:  STRINGDB
CCDC124
Tdark
Novelty:  0.72482697
Score:  0.718
Data Source:  STRINGDB
OFD1
Tbio
Novelty:  0.01032841
Score:  0.692
Data Source:  STRINGDB
TUBGCP2
Tbio
Novelty:  0.01856674
Score:  0.68
Data Source:  STRINGDB
CDKN3
Tbio
Family:  Enzyme
Novelty:  0.00093913
Score:  0.67
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
3
2
2
23.2
95.6
heel bone mineral density
3
3
4
94.5
sclerostin measurement
1
1
1
84
body height
2
3
3
81.8
BMI-adjusted waist circumference
2
5
5
80
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
2
23.2
95.6
heel bone mineral density
4
94.5
sclerostin measurement
1
84
body height
3
81.8
BMI-adjusted waist circumference
5
80
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 77
VGNC:5326
746193
Macaque
coiled-coil domain containing 77
721604
Mouse
MGI:1914450
67200
Rat
RGD:1310710
312677
Dog
coiled-coil domain containing 77
VGNC:38855
486749
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 77
Macaque
coiled-coil domain containing 77
Mouse
Rat
Dog
coiled-coil domain containing 77
Publication Statistics
PubMed Score 0.20
PubMed score by year
PubTator Score 0.09
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title