You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
CBWD1
COBW domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314367
  • ENSP00000323433
  • ENSG00000172785
  • ENST00000356521
  • ENSP00000348915
  • ENST00000377400
  • ENSP00000366617
  • ENST00000382393
  • ENSP00000371830
  • ENST00000382447
  • ENSP00000371885

Symbol
  • COBP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.95
transcription factor perturbation
0.8
molecular function
0.73
tissue
0.67
cell line
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 160   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 160   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (77)
METAP1
Tchem
Family:  Enzyme
Novelty:  0.01816253
p_int:  0.999999907
p_ni:  9.3e-8
Score:  0.473
Data Source:  BioPlex,STRINGDB
CBWD6
Tdark
Novelty:  8.14063875
p_int:  0.99999988
p_ni:  1.2e-7
Score:  0.554
Data Source:  BioPlex,STRINGDB
CBWD2
Tdark
Novelty:  5.35433071
p_int:  0.999999868
p_ni:  1.32e-7
Score:  0.586
Data Source:  BioPlex,STRINGDB
AGAP1
Tbio
Family:  Enzyme
Novelty:  0.06776705
p_int:  0.998599306
p_ni:  0.001213638
p_wrong:  0.000187055
Score:  0.159
Data Source:  BioPlex,STRINGDB
UXS1
Tbio
Family:  Enzyme
Novelty:  0.04671281
p_int:  0.996434366
p_ni:  0.003565476
p_wrong:  1.57e-7
Data Source:  BioPlex
SPANXB1
Tbio
Novelty:  0.19187624
p_int:  0.990513625
p_ni:  0.009486375
Data Source:  BioPlex
SFTA2
Tdark
Novelty:  0.24469271
p_int:  0.990101221
p_ni:  0.009898779
Data Source:  BioPlex
SAMD1
Tdark
Novelty:  0.21956379
p_int:  0.989863394
p_ni:  0.010136604
p_wrong:  2e-9
Score:  0.21
Data Source:  BioPlex,STRINGDB
DKKL1
Tbio
Novelty:  0.00544618
p_int:  0.98745597
p_ni:  0.01254403
Data Source:  BioPlex
TCERG1
Tbio
Novelty:  0.01721248
p_int:  0.987294181
p_ni:  0.012705819
Score:  0.665
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
5
5
96.9
red blood cell distribution width
2
2
2
86.6
hair color
2
2
0
1.1
79.7
platelet count
1
1
1
64
balding measurement
1
1
1
55.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
5
96.9
red blood cell distribution width
2
86.6
hair color
0
1.1
79.7
platelet count
1
64
balding measurement
1
55.2
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
COBW domain containing 1
698333
Species
Name
OMA
EggNOG
Inparanoid
Macaque
COBW domain containing 1
Publication Statistics
PubMed Score 23.47
PubMed score by year
PubTator Score 8.67
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title