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Tdark
C6orf141
Uncharacterized protein C6orf141

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371194
  • ENSP00000431184
  • ENSG00000197261
  • ENST00000414696
  • ENSP00000436754
  • ENST00000529246
  • ENSP00000434602
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (86)
MORC3
Tbio
Novelty:  0.01216555
p_int:  0.999999566
p_ni:  4.34e-7
Score:  0.188
Data Source:  BioPlex,STRINGDB
PLEC
Tbio
Novelty:  0.00223244
p_int:  0.999985129
p_ni:  0.000014871
Data Source:  BioPlex
KIAA0586
Tbio
Novelty:  0.0346398
p_int:  0.999984927
p_ni:  0.000015049
p_wrong:  2.4e-8
Data Source:  BioPlex
PLCH1
Tbio
Family:  Enzyme
Novelty:  0.11128204
p_int:  0.99984698
p_ni:  0.000148762
p_wrong:  0.000004257
Data Source:  BioPlex
FAM83H
Tbio
Novelty:  0.02527211
p_int:  0.999236701
p_ni:  0.000763299
Data Source:  BioPlex
PRR14
Tbio
Novelty:  0.22401806
p_int:  0.999069899
p_ni:  0.000120023
p_wrong:  0.000810077
Data Source:  BioPlex
CAMKK2
Tchem
Family:  Kinase
Novelty:  0.00426898
p_int:  0.998903756
p_ni:  0.001075597
p_wrong:  0.000020647
Data Source:  BioPlex
ALMS1
Tbio
Novelty:  0.00694228
p_int:  0.998432394
p_ni:  0.001567488
p_wrong:  1.19e-7
Data Source:  BioPlex
SMG7
Tbio
Novelty:  0.03394393
p_int:  0.998393677
p_ni:  0.001606306
p_wrong:  1.8e-8
Data Source:  BioPlex
ZNF195
Tdark
Family:  TF
Novelty:  0.23029736
p_int:  0.996806155
p_ni:  0.003189236
p_wrong:  0.000004609
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
2
2
82.3
mean reticulocyte volume
1
2
2
57.1
reticulocyte measurement
1
1
1
13.8
reticulocyte count
1
1
1
13.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
2
82.3
mean reticulocyte volume
2
57.1
reticulocyte measurement
1
13.8
reticulocyte count
1
13.6
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 6 C6orf141 homolog
VGNC:12619
462755
Mouse
MGI:1918833
71583
Rat
RGD:1588829
688459
Horse
chromosome 20 C6orf141 homolog
VGNC:52316
100630552
Cow
chromosome 23 C6orf141 homolog
VGNC:52676
100271839
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 6 C6orf141 homolog
Mouse
Rat
Horse
chromosome 20 C6orf141 homolog
Cow
chromosome 23 C6orf141 homolog
Publication Statistics
PubMed Score 1.26
PubMed score by year
PubTator Score 0.44
PubTator score by year
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Related Publications
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PMID
Year
Title