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Tbio
C17orf80
Uncharacterized protein C17orf80

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000268942
  • ENSP00000268942
  • ENSG00000141219
  • ENST00000359042
  • ENSP00000351937
  • ENST00000426147
  • ENSP00000396970
  • ENST00000535032
  • ENSP00000440551
  • ENST00000577615
  • ENSP00000464132

Symbol
  • MIG3
  • HLC-8
  • SPEP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.36   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.36   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (70)
HADHA
Tbio
Novelty:  0.00385746
p_int:  0.999973003
p_ni:  0.000026982
p_wrong:  1.5e-8
Data Source:  BioPlex
KCNA5
Tclin
Family:  IC
Novelty:  0.00182891
p_int:  0.999939643
p_ni:  0.00005396
p_wrong:  0.000006397
Data Source:  BioPlex
IL13RA2
Tbio
Novelty:  0.03465642
p_int:  0.999808813
p_ni:  0.000191187
Data Source:  BioPlex
CD44
Tbio
Novelty:  0.00011321
p_int:  0.999781619
p_ni:  0.000218381
Data Source:  BioPlex
IL7R
Tbio
Novelty:  0.00107223
p_int:  0.998945255
p_ni:  0.001054745
Data Source:  BioPlex
PMEL
Tbio
Novelty:  0.00116525
p_int:  0.996622811
p_ni:  0.003377042
p_wrong:  1.48e-7
Data Source:  BioPlex
Q8NFQ8
Tbio
Novelty:  0.08912351
p_int:  0.990856327
p_ni:  0.009143673
Data Source:  BioPlex
SUCLA2
Tchem
Family:  Enzyme
Novelty:  0.02029861
p_int:  0.985856379
p_ni:  0.014143621
Data Source:  BioPlex
SPACA1
Tbio
Novelty:  0.07415851
p_int:  0.983939162
p_ni:  0.016060838
Score:  0.226
Data Source:  BioPlex,STRINGDB
LRP1
Tbio
Novelty:  0.00200788
p_int:  0.965037769
p_ni:  0.034962231
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
2
3
79.2
mean reticulocyte volume
1
1
1
74.6
mean corpuscular volume
1
1
1
71.9
mean corpuscular hemoglobin concentration
1
1
1
64.9
reticulocyte count
2
2
2
57.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
79.2
mean reticulocyte volume
1
74.6
mean corpuscular volume
1
71.9
mean corpuscular hemoglobin concentration
1
64.9
reticulocyte count
2
57.6
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 17 C17orf80 homolog
VGNC:10099
454858
Macaque
chromosome 16 open reading frame, human C17orf80
695988
Mouse
MGI:106356
276852
Rat
RGD:1359207
287798
Dog
chromosome 9 C17orf80 homolog
VGNC:49208
610011
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 17 C17orf80 homolog
Macaque
chromosome 16 open reading frame, human C17orf80
Mouse
Rat
Dog
chromosome 9 C17orf80 homolog
Publication Statistics
PubMed Score 5.36
PubMed score by year
PubTator Score 2.20
PubTator score by year
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Related Publications
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PMID
Year
Title