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Tdark
BPIFC
BPI fold-containing family C protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300399
  • ENSP00000300399
  • ENSG00000184459
  • ENST00000397452
  • ENSP00000380594
  • ENST00000534972
  • ENSP00000439123

Symbol
  • BPIL2
  • BPIL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.92
virus perturbation
0.59
protein domain
0.58
cell line
0.49
tissue sample
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.61   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.61   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (12)
DHRS9
Tbio
Family:  Enzyme
Novelty:  0.00256743
Score:  0.606
Data Source:  STRINGDB
BPIFA1
Tbio
Novelty:  0.00586117
Score:  0.605
Data Source:  STRINGDB
PLEKHA4
Tbio
Novelty:  0.53027856
Score:  0.601
Data Source:  STRINGDB
IQCD
Tbio
Novelty:  0.21789956
Score:  0.59
Data Source:  STRINGDB
CDK5RAP1
Tbio
Novelty:  0.0347805
Score:  0.514
Data Source:  STRINGDB
PRR34
Tdark
Novelty:  0.51746018
Score:  0.511
Data Source:  STRINGDB
BPIFB1
Tbio
Novelty:  0.03980683
Score:  0.508
Data Source:  STRINGDB
RFPL2
Tdark
Novelty:  1.87914964
Score:  0.477
Data Source:  STRINGDB
RFPL3
Tbio
Novelty:  0.44520296
Score:  0.473
Data Source:  STRINGDB
NRIP1
Tbio
Novelty:  0.00551568
Score:  0.471
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
3
4
4
96.5
mean corpuscular hemoglobin concentration
2
2
2
95.6
red blood cell distribution width
4
3
4
94.6
mean reticulocyte volume
1
2
2
87.3
red blood cell density measurement
1
1
1
84.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
4
96.5
mean corpuscular hemoglobin concentration
2
95.6
red blood cell distribution width
4
94.6
mean reticulocyte volume
2
87.3
red blood cell density measurement
1
84.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
BPI fold containing family C
VGNC:5230
738942
Macaque
BPI fold containing family C
717287
Mouse
MGI:3026884
270757
Rat
RGD:1311686
299685
Dog
BPI fold containing family C
VGNC:38512
474523
Species
Name
OMA
EggNOG
Inparanoid
Chimp
BPI fold containing family C
Macaque
BPI fold containing family C
Mouse
Rat
Dog
BPI fold containing family C
Publication Statistics
PubMed Score 2.61
PubMed score by year
PubTator Score 0.87
PubTator score by year
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Related Publications
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PMID
Year
Title