You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
BCL2L13
Bcl-2-like protein 13

Protein Summary
Description
May promote the activation of caspase-3 and apoptosis. This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000317582
  • ENSP00000318883
  • ENSG00000099968
  • ENST00000399782
  • ENSP00000382682
  • ENST00000418951
  • ENSP00000410019
  • ENST00000493680
  • ENSP00000434764
  • ENST00000543133
  • ENSP00000437667

Symbol
  • MIL1
  • MIL1
  • BCL-RAMBO
  • Bcl2-L-13
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.99
transcription factor perturbation
0.94
virus perturbation
0.9
transcription factor binding site profile
0.85
kinase perturbation
0.76


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.55   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 250   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.55   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 250   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0