You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
B4GALNT4
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1

Protein Summary
Description
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329962
  • ENSP00000328277
  • ENSG00000182272
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.65
transcription factor
0.59
cellular component
0.58
PubMedID
0.58
histone modification site profile
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.99   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.99   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (48)
PILRA
Tbio
Novelty:  0.05154386
p_int:  0.999999262
p_ni:  7.37e-7
p_wrong:  1e-9
Score:  0.52
Data Source:  BioPlex,STRINGDB
CSN1S1
Tbio
Family:  Enzyme
Novelty:  0.00200522
p_int:  0.998772617
p_ni:  0.000704747
p_wrong:  0.000522636
Score:  0.187
Data Source:  BioPlex,STRINGDB
LYZL2
Tdark
Family:  Enzyme
Novelty:  0.50542161
p_int:  0.998772617
p_ni:  0.000704747
p_wrong:  0.000522636
Data Source:  BioPlex
ANTXR1
Tbio
Novelty:  0.00508081
p_int:  0.963665579
p_ni:  0.00004201
p_wrong:  0.036292412
Score:  0.218
Data Source:  BioPlex,STRINGDB
INSL5
Tbio
Novelty:  0.04351334
p_int:  0.95805752
p_ni:  0.000057456
p_wrong:  0.041885025
Data Source:  BioPlex
INS
Tbio
Novelty:  0.00000499
p_int:  0.878011165
p_ni:  0.000542852
p_wrong:  0.121445982
Data Source:  BioPlex
PGGHG
Tbio
Family:  Enzyme
Novelty:  0.40196205
Score:  0.858
Data Source:  STRINGDB
B4GALNT3
Tbio
Family:  Enzyme
Novelty:  0.1822928
Score:  0.815
Data Source:  STRINGDB
C1QTNF4
Tbio
Novelty:  0.10701626
Score:  0.756
Data Source:  STRINGDB
MXRA7
Tdark
Novelty:  0.20850504
Score:  0.673
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (32)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
3
3
3
17.9
96.7
eosinophil count
3
3
4
96.7
eosinophil percentage of leukocytes
2
4
4
96.5
monocyte percentage of leukocytes
2
3
4
96.2
leukocyte count
2
3
3
96.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
3
17.9
96.7
eosinophil count
4
96.7
eosinophil percentage of leukocytes
4
96.5
monocyte percentage of leukocytes
4
96.2
leukocyte count
3
96.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
beta-1,4-N-acetyl-galactosaminyltransferase 4
VGNC:7796
450920
Macaque
beta-1,4-N-acetyl-galactosaminyltransferase 4
720768
Mouse
MGI:2652891
330671
Rat
RGD:1310052
309105
Dog
beta-1,4-N-acetyl-galactosaminyltransferase 4
VGNC:38348
483398
Species
Name
OMA
EggNOG
Inparanoid
Chimp
beta-1,4-N-acetyl-galactosaminyltransferase 4
Macaque
beta-1,4-N-acetyl-galactosaminyltransferase 4
Mouse
Rat
Dog
beta-1,4-N-acetyl-galactosaminyltransferase 4
Publication Statistics
PubMed Score 4.99
PubMed score by year
PubTator Score 1.75
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title