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Tdark
NUTM2E
NUT family member 2E

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000429984
  • ENSP00000407521
  • ENSG00000228570

Symbol
  • FAM22E
  • FAM22E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.84
cell type or tissue
0.81
tissue
0.47
tissue sample
0.43
cell line
0.14


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.28   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.28   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
FEV/FEC ratio
1
1
1
64.4
1
1
0
1.2
26.1
2
1
0
1.1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
FEV/FEC ratio
1
64.4
0
1.2
26.1
0
1.1
21.5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-B1AL46-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (2)
1 – 2 of 2
YWHAE
Tbio
Novelty:  0.00431876
Score:  0.522
Data Source:  STRINGDB
IRX2
Tbio
Family:  TF
Novelty:  0.0289211
Score:  0.43
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.28

PubMed score by year
PubTator Score  0.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer