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Tdark
TMEM200C
Transmembrane protein 200C

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000383490
  • ENSP00000372982
  • ENSG00000206432
  • ENST00000581347
  • ENSP00000463375

Symbol
  • TTMA
  • TTMA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.65
cell line
0.47
tissue
0.47
transcription factor perturbation
0.4
cellular component
0.34


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
3
2
3
72.1
smoking status measurement
2
2
2
64.8
self reported educational attainment
1
1
1
61.4
cognitive function measurement
1
1
1
40.7
smoking initiation
1
1
1
27.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
3
72.1
smoking status measurement
2
64.8
self reported educational attainment
1
61.4
cognitive function measurement
1
40.7
smoking initiation
1
27.3
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 200C
VGNC:13293
455308
Mouse
MGI:3646281
622645
Rat
RGD:1561734
501201
Cow
transmembrane protein 200C
VGNC:54501
786855
Opossum
transmembrane protein 200C
100012648
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 200C
Mouse
Rat
Cow
transmembrane protein 200C
Opossum
transmembrane protein 200C
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NKL6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (18)
1 – 10 of 18
TMC6
Tbio
Family:  IC
Novelty:  0.00761789
Score:  0.643
Data Source:  STRINGDB
ARHGAP8
Tbio
Family:  Enzyme
Novelty:  0.22016818
Score:  0.62
Data Source:  STRINGDB
TMEM174
Tdark
Novelty:  0.40496536
Score:  0.558
Data Source:  STRINGDB
PTMS
Tbio
Novelty:  0.02576053
Score:  0.542
Data Source:  STRINGDB
ACER3
Tbio
Family:  Enzyme
Novelty:  0.01058501
Score:  0.537
Data Source:  STRINGDB
SPAG17
Tdark
Novelty:  0.03260168
Score:  0.53
Data Source:  STRINGDB
L3MBTL4
Tbio
Family:  TF; Epigenetic
Novelty:  0.1892631
Score:  0.53
Data Source:  STRINGDB
VPS11
Tbio
Novelty:  0.00496411
Score:  0.525
Data Source:  STRINGDB
RNF165
Tdark
Novelty:  0.83518935
Score:  0.52
Data Source:  STRINGDB
PRELID3A
Tbio
Novelty:  1.54594896
Score:  0.519
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.81

PubMed score by year
PubTator Score  5.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer