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Tdark
PCNX2
Pecanex-like protein 2

Protein Summary
Description
May play a role in tumorigenesis of colorectal carcinomas with high microsatellite instability (MSI-H). This gene contains coding mononucleotide repeats that are associated with tumors of high mcrosatellite instability (MSI-H). Defects in this gene are involved in the tumorigenesis of MSI-H colorectal carcinomas. [provided by RefSeq, Jun 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258229
  • ENSP00000258229
  • ENSG00000135749
  • ENST00000344698
  • ENSP00000340759

Symbol
  • KIAA0435
  • PCNXL2
  • PCNXL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.4   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.4   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (18)
1 – 10 of 18
HEPH
Tbio
Novelty: 0.00614226
Score: 0.686
Data Source: STRINGDB
PLPP4
Tbio
Family: Enzyme
Novelty: 0.36878578
Score: 0.589
Data Source: STRINGDB
GPR179
Tdark
Family: GPCR
Novelty: 0.12764018
Score: 0.587
Data Source: STRINGDB
CREM
Tbio
Family: TF
Novelty: 0.00090177
Score: 0.561
Data Source: STRINGDB
ADGRL3
Tbio
Family: GPCR
Novelty: 0.00182297
Score: 0.549
Data Source: STRINGDB
PLPP5
Tbio
Family: Enzyme
Novelty: 0.17356459
Score: 0.536
Data Source: STRINGDB
EML6
Tdark
Novelty: 1.71428571
Score: 0.501
Data Source: STRINGDB
KIAA0319
Tbio
Novelty: 0.01891752
Score: 0.493
Data Source: STRINGDB
TAF1B
Tbio
Family: Enzyme
Novelty: 0.13655576
Score: 0.47
Data Source: STRINGDB
NXPH2
Tdark
Novelty: 0.61538462
Score: 0.461
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.40

PubMed score by year
PubTator Score  0.71

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer