desvenlafaxine
Ligand Summary
The exact mechanism of the antidepressant action of desvenlafaxine is unknown, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake. Non-clinical studies have shown that desvenlafaxine is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI).
UNII: NG99554ANW
PubChem: 125017
Guide to Pharmacology: 7158
ChEMBL: CHEMBL1118
DrugCentral: 4380
LyCHI: ZXZGA28FC1D5
Target Activities
9 Activities
Items per page:
1 – 9 of 9
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | ||||||
Ki | ||||||
Ki | ||||||
Ki | ||||||
IC50 | ||||||
IC50 | ||||||
IC50 | ||||||
Ki | INHIBITOR | |||||
Ki | INHIBITOR | |||||