CHEMBL3960724
Ligand Summary
Name: 1-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-(thiophene-2-sulfonyl)piperazine
PubChem: 77846790
ChEMBL: CHEMBL3960724
LyCHI: SC66FK4WK4A1
Target Activities
CYP3A4
Cytochrome P450 3A4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.06 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.05 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP11B1
Cytochrome P450 11B1, mitochondrial
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.09 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP21A2
Steroid 21-hydroxylase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.83 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||