CHEMBL179552
Ligand Summary
Name: (2R,5R)-1-(4-(2,4-dichlorobenzyloxy)phenylsulfonyl)-N,5-dihydroxy-3,3-dimethylpiperidine-2-carboxamide
PubChem: 11752434
ChEMBL: CHEMBL179552
LyCHI: FF4XM63AJQNN
Target Activities
MMP1
Interstitial collagenase
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.7 | None, (2001) None:None:None | ||||
IC50 | 6.7 | |||||
IC50 | 6.37 | Bioorg. Med. Chem. Lett., (2005) 15:11:2808 | ||||
ADAMTS5
A disintegrin and metalloproteinase with thrombospondin motifs 5
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.85 | J. Med. Chem., (2011) 54:8:2839 | ||||
ADAMTS4
A disintegrin and metalloproteinase with thrombospondin motifs 4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.96 | J. Med. Chem., (2011) 54:8:2839 | ||||
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.72 | Bioorg. Med. Chem. Lett., (2005) 15:11:2808 | ||||
MMP13
Collagenase 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.52 | Bioorg. Med. Chem. Lett., (2005) 15:11:2808 | ||||