OTS-167
Ligand Summary
Target Activities
MELK
Maternal embryonic leucine zipper kinase
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.4 | None, (2015) None:None:None | ||||
IC50 | 9.39 | MedChemComm, (2017) 8:1:73 | ||||
IC50 | 8.96 | None, (2015) None:None:None | ||||
Kd | 7.82 | Bioorg Med Chem, (2020) 28:1:115193 | ||||
Kd | 7.54 | Science, (2017) 358:6367:None | ||||
DYRK1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3 Activities
PRKAG2
5'-AMP-activated protein kinase subunit gamma-2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.68 | Science, (2017) 358:6367:None | ||||
PIM1
Serine/threonine-protein kinase pim-1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.85 | Science, (2017) 358:6367:None | ||||
STK10
Serine/threonine-protein kinase 10
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.85 | Science, (2017) 358:6367:None | ||||
CSNK2A2
Casein kinase II subunit alpha'
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8 | Science, (2017) 358:6367:None | ||||
CLK1
Dual specificity protein kinase CLK1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.96 | Science, (2017) 358:6367:None | ||||
GAK
Cyclin-G-associated kinase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.3 | Science, (2017) 358:6367:None | ||||
EPHA7
Ephrin type-A receptor 7
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.8 | Science, (2017) 358:6367:None | ||||
RIPK2
Receptor-interacting serine/threonine-protein kinase 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.3 | Science, (2017) 358:6367:None | ||||
IRAK3
Interleukin-1 receptor-associated kinase 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.92 | Science, (2017) 358:6367:None | ||||
BCR
Breakpoint cluster region protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.85 | Science, (2017) 358:6367:None | ||||
TAOK1
Serine/threonine-protein kinase TAO1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.77 | Science, (2017) 358:6367:None | ||||
NLK
Serine/threonine-protein kinase NLK
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.62 | Science, (2017) 358:6367:None | ||||
BMPR1B
Bone morphogenetic protein receptor type-1B
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.7 | Science, (2017) 358:6367:None | ||||
TAOK3
Serine/threonine-protein kinase TAO3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.68 | Science, (2017) 358:6367:None | ||||
TAOK2
Serine/threonine-protein kinase TAO2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8 | Science, (2017) 358:6367:None | ||||
LATS1
Serine/threonine-protein kinase LATS1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.85 | Science, (2017) 358:6367:None | ||||
PIP4K2C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.52 | Science, (2017) 358:6367:None | ||||
DHX30
ATP-dependent RNA helicase DHX30
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.22 | Science, (2017) 358:6367:None | ||||
Uncharacterized protein FLJ45252
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.81 | Science, (2017) 358:6367:None | ||||
RET
Proto-oncogene tyrosine-protein kinase receptor Ret
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.55 | Science, (2017) 358:6367:None | ||||