| Tdark | Zinc finger protein 184 |
May be involved in transcriptional regulation.
The protein encoded by this gene is predicted to be a Kruppel C2H2-type zinc-finger protein family member. Sequence analysis predicts that the protein contains two Kruppel associated box (KRAB) boxes in the N-terminus and highly conserved zinc finger motifs at the C-terminus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
The protein encoded by this gene is predicted to be a Kruppel C2H2-type zinc-finger protein family member. Sequence analysis predicts that the protein contains two Kruppel associated box (KRAB) boxes in the N-terminus and highly conserved zinc finger motifs at the C-terminus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 5112 | 1.7e-03 |
| astrocytic glioma | 2597 | 7.1e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 8.6e-03 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 1.8e-02 |
| medulloblastoma, large-cell | 6241 | 2.5e-02 |
| oligodendroglioma | 2850 | 3.6e-02 |
| ependymoma | 4679 | 3.8e-02 |
| Disease | log2 FC | p |
|---|---|---|
| astrocytic glioma | -1.500 | 7.1e-03 |
| atypical teratoid / rhabdoid tumor | -1.100 | 1.7e-03 |
| ependymoma | -1.100 | 3.8e-02 |
| intraductal papillary-mucinous adenoma (... | 1.200 | 8.6e-03 |
| intraductal papillary-mucinous carcinoma... | 1.300 | 1.8e-02 |
| medulloblastoma, large-cell | -1.100 | 2.5e-02 |
| oligodendroglioma | -1.200 | 3.6e-02 |
MEDLSSPDSTLLQGGHNLLSSASFQEAVTFKDVIVDFTQEEWKQLDPGQRDLFRDVTLENYTHLVSIGLQ 1 - 70 VSKPDVISQLEQGTEPWIMEPSIPVGTCADWETRLENSVSAPEPDISEEELSPEVIVEKHKRDDSWSSNL 71 - 140 LESWEYEGSLERQQANQQTLPKEIKVTEKTIPSWEKGPVNNEFGKSVNVSSNLVTQEPSPEETSTKRSIK 141 - 210 QNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKC 211 - 280 DQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFM 281 - 350 EHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYEC 351 - 420 NECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLT 421 - 490 QHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQC 491 - 560 HECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLA 561 - 630 QHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGEKPYNC 631 - 700 NECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLHPGI 701 - 751 //
