| Tdark | Mitochondrial import receptor subunit TOM40B |
Potential channel-forming protein implicated in import of protein precursors into mitochondria.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung adenocarcinoma | 2714 | 5.8e-13 |
| osteosarcoma | 7933 | 7.7e-05 |
| medulloblastoma | 1524 | 8.7e-05 |
| atypical teratoid / rhabdoid tumor | 4369 | 2.3e-04 |
| medulloblastoma, large-cell | 6234 | 5.2e-04 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3289 | 1.3e-03 |
| tuberculosis | 1563 | 2.1e-03 |
| glioblastoma | 5572 | 3.2e-03 |
| astrocytic glioma | 2241 | 9.4e-03 |
| ependymoma | 2514 | 1.6e-02 |
| oligodendroglioma | 2849 | 4.1e-02 |
| Disease | log2 FC | p |
|---|---|---|
| astrocytic glioma | -1.400 | 9.4e-03 |
| ependymoma | -1.800 | 1.6e-02 |
| oligodendroglioma | -1.100 | 4.1e-02 |
| osteosarcoma | -1.994 | 7.7e-05 |
| atypical teratoid / rhabdoid tumor | -1.400 | 2.3e-04 |
| glioblastoma | -1.100 | 3.2e-03 |
| medulloblastoma | -1.200 | 8.7e-05 |
| medulloblastoma, large-cell | -1.300 | 5.2e-04 |
| tuberculosis | 1.100 | 2.1e-03 |
| intraductal papillary-mucinous neoplasm ... | 1.200 | 1.3e-03 |
| lung adenocarcinoma | 1.100 | 5.8e-13 |
MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTIHMSA 1 - 70 LGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGE 71 - 140 YRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATL 141 - 210 NVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMP 211 - 280 PLPVTLALGAFLNHWRNRFHCGFSITVG 281 - 308 //
| PMID | Year | Title | |
|---|---|---|---|
| 25944712 | 2015 | N-terminome analysis of the human mitochondrial proteome. | |
| 24816252 | 2014 | An atlas of genetic influences on human blood metabolites. | |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | |
| 17974005 | 2007 | The full-ORF clone resource of the German cDNA Consortium. | |
| 16959974 | 2006 | The consensus coding sequences of human breast and colorectal cancers. | |
| 16710414 | 2006 | The DNA sequence and biological annotation of human chromosome 1. | |
| 16381901 | 2006 | The LIFEdb database in 2006. | |
| 16344560 | 2006 | Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. | |
| 15489336 | 2004 | From ORFeome to biology: a functional genomics pipeline. | |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. | |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | |
| 11256614 | 2000 | Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. | |
| 11230166 | 2001 | Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. | |
| 11076863 | 2000 | DNA cloning using in vitro site-specific recombination. |
