Protein Summary
May play a role in both peripheral and central nervous system development. This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development. [provided by RefSeq, Jul 2008]
- ENST00000586582
- ENSP00000467290
- ENSG00000167680
- ENST00000586965
- ENSP00000465722
- SEMAN
- SEMAZ
- SEMAN
- semaZ
- SEMA-VIB
- SEM-SEMA-Y
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.73 | ||
tissue sample | 0.64 | ||
cell type or tissue | 0.56 | ||
transcription factor | 0.53 | ||
gene perturbation | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 70.85 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 96 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 70.85 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 96 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0