Property Summary

NCBI Gene PubMed Count 8
PubMed Score 77.33
PubTator Score 17.06

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
malignant mesothelioma 3163 1.63788480084788E-6
group 3 medulloblastoma 2254 0.00126335817359232
lung cancer 4473 0.00179057071678722
Multiple myeloma 1328 0.00309999467786866
invasive ductal carcinoma 2950 0.0126918486422672
Disease Target Count Z-score Confidence
Tarsal tunnel syndrome 4 4.58 2.3

Expression

  Differential Expression (5)

Disease log2 FC p
Multiple myeloma 1.399 0.003
malignant mesothelioma -1.400 0.000
lung cancer 1.600 0.002
group 3 medulloblastoma 1.200 0.001
invasive ductal carcinoma 1.200 0.013

Synonym

Accession Q9UBI1 D3DRU7 Q5T8Y9
Symbols BUP
C10orf8

Gene

  Ortholog (11)

Species Source
Chimp OMA EggNOG
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog OMA EggNOG Inparanoid
Horse OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Pig OMA EggNOG
Platypus OMA EggNOG
Anole lizard OMA EggNOG Inparanoid
Zebrafish OMA EggNOG Inparanoid
Fruitfly EggNOG Inparanoid

AA Sequence

MELSESVQKGFQMLADPRSFDSNAFTLLLRAAFQSLLDAQADEAVLDHPDLKHIDPVVLKHCHAAAATYI      1 - 70
LEAGKHRADKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLEILLGSIGRSLPHITDVSWRLEYQIKTNQ     71 - 140
LHRMYRPAYLVTLSVQNTDSPSYPEISFSCSMEQLQDLVGKLKDASKSLERATQL                   141 - 195
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Text Mined References (12)

PMID Year Title
26496610 2015 A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25355947 2015 COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.
23637203 2013 Functional interaction of COMMD3 and COMMD9 with the epithelial sodium channel.
23563313 2013 CCDC22 deficiency in humans blunts activation of proinflammatory NF-?B signaling.
21778237 2011 COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.
21269460 2011 Initial characterization of the human central proteome.
15799966 2005 COMMD proteins, a novel family of structural and functional homologs of MURR1.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15164054 2004 The DNA sequence and comparative analysis of human chromosome 10.
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