Property Summary

NCBI Gene PubMed Count 7
Grant Count 7
R01 Count 4
Funding $923,745.16
PubMed Score 4.79
PubTator Score 1.53

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (15)

Disease log2 FC p
gastric cancer 1.100 0.003
ependymoma -2.600 0.000
glioblastoma -2.600 0.000
medulloblastoma -2.100 0.000
cystic fibrosis 1.485 0.000
atypical teratoid / rhabdoid tumor -3.800 0.000
medulloblastoma, large-cell -3.300 0.000
primitive neuroectodermal tumor -1.400 0.001
Breast cancer 2.300 0.046
pediatric high grade glioma -1.900 0.000
subependymal giant cell astrocytoma -1.268 0.023
lung carcinoma 1.600 0.000
ductal carcinoma in situ -1.200 0.002
invasive ductal carcinoma -1.500 0.002
ovarian cancer -2.800 0.000

Gene RIF (1)

PMID Text
15095301 levels of TM1, TM2 and TM3 are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase-signaling pathway

AA Sequence

MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLL      1 - 70
MYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGV     71 - 140
HNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNI    141 - 210
PIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKE    211 - 280
NDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADR    281 - 350
R//

Text Mined References (8)

PMID Year Title
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16572171 2006 Analysis of the DNA sequence and duplication history of human chromosome 15.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15095301 2004 Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
10662549 2000 Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs.