| Tbio | Polycystic kidney disease 2-like 2 protein |
May function as a subunit of a cation channel and play a role in fertilization.
Comments
| Disease | Z-score | Confidence |
|---|---|---|
| Polycystic kidney disease 54 | 4.706 | 2.4 |
| osteosarcoma 7,933 | ||
| ovarian cancer 8,484 |
MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSV 1 - 70 PGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNT 71 - 140 CKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSE 141 - 210 TKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDY 211 - 280 FIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLK 281 - 350 STEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFA 351 - 420 YAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAII 421 - 490 NDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDENEIQ 491 - 560 NAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYAVELEKELHYINLKLNQVVRKVSAL 561 - 624 //
| PMID | Year | Title |
|---|---|---|
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| 15372022 | 2004 | The DNA sequence and comparative analysis of human chromosome 5. |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
| 11959145 | 2002 | The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation. |
| 11698076 | 2001 | Polycystin channels and kidney disease. |
| 10756092 | 2000 | Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization. |
| 10602361 | 1999 | Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2). |
