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  4. Polycystin cation channel (pcc) family
  5. Polycystic kidney disease 2-like 2 protein

Tdark Polycystic kidney disease 2-like 2 protein

May function as a subunit of a cation channel and play a role in fertilization.

 Comments

Property Summary

NCBI Gene PubMed Count 5
PubMed Score 4.79
PubTator Score 2.99

Knowledge Summary

Patent (647)

TINX Plot

  Disease (3)

Disease Target Count P-value
ovarian cancer 8520 3.7e-08
osteosarcoma 7950 3.5e-07
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.9
Kidney cancer 2613 0.0 0.6

Expression

  Differential Expression (2)

Disease log2 FC p
osteosarcoma -1.458 3.5e-07
ovarian cancer -1.800 3.7e-08

Synonym

Accession Q9NZM6 A6NK98 B4DXD2 E9PC91 E9PDG4 Q86YB4 Q9UNJ0
Symbols TRPP5

Gene

PKD2L2

PANTHER Protein Class (2)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 Collection (1)

 UniProt Keyword (12)

See all...

 GO Function (2)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (8)

 IMPC Phenotype (3)

 MGI Phenotype (2)

 GWAS Trait (1)

 HCA RNA Cell Line (56)

See all...

Protein-protein Interaction (4)

PKD2   SERPINB4   SERPINB3   CCPG1  

AA Sequence 

MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSV      1 - 70
PGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNT     71 - 140
CKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSE    141 - 210
TKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDY    211 - 280
FIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLK    281 - 350
STEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFA    351 - 420
YAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAII    421 - 490
NDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDENEIQ    491 - 560
NAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYAVELEKELHYINLKLNQVVRKVSAL          561 - 624
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Text Mined References (8)

PMID Year Title