Property Summary

NCBI Gene PubMed Count 10
PubMed Score 0.17
PubTator Score 0.33

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
ovarian cancer 8492 5.081322570258E-4
primary Sjogren syndrome 789 9.3245185623159E-4
lung cancer 4473 9.62924404499453E-4
hereditary spastic paraplegia 313 0.0074929422782779
Waldenstrons macroglobulinemia 765 0.024776775255027

Expression

  Differential Expression (5)

Disease log2 FC p
Waldenstrons macroglobulinemia 1.119 0.025
hereditary spastic paraplegia -1.192 0.007
lung cancer 1.500 0.001
primary Sjogren syndrome 1.300 0.001
ovarian cancer -1.400 0.001

Synonym

Accession Q9NX08 Q8WUR4 Q9HC15
Symbols

Gene

  Ortholog (12)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog OMA EggNOG Inparanoid
Horse OMA EggNOG
Cow OMA EggNOG Inparanoid
Opossum OMA EggNOG Inparanoid
Platypus OMA EggNOG
Chicken OMA Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid

Gene RIF (1)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence

MEPEEGTPLWRLQKLPAELGPQLLHKIIDGICGRAYPVYQDYHTVWESEEWMHVLEDIAKFFKAIVGKNL      1 - 70
PDEEIFQQLNQLNSLHQETIMKCVKSRKDEIKQALSREIVAISSAQLQDFDWQVKLALSSDKIAALRMPL     71 - 140
LSLHLDVKENGEVKPYSIEMSREELQNLIQSLEAANKVVLQLK                               141 - 183
//

Text Mined References (13)

PMID Year Title
26496610 2015 A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25355947 2015 COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.
23637203 2013 Functional interaction of COMMD3 and COMMD9 with the epithelial sodium channel.
23563313 2013 CCDC22 deficiency in humans blunts activation of proinflammatory NF-?B signaling.
21778237 2011 COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.
21269460 2011 Initial characterization of the human central proteome.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
15799966 2005 COMMD proteins, a novel family of structural and functional homologs of MURR1.
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