Property Summary

NCBI Gene PubMed Count 11
PubMed Score 33.00
PubTator Score 13.33

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
glioblastoma 5572 4.95675109577101E-9
group 3 medulloblastoma 2254 3.92236177526627E-7
atypical teratoid/rhabdoid tumor 1095 2.0513102140361E-6
adult high grade glioma 2148 5.80131308804283E-6
primitive neuroectodermal tumor 3031 6.60647694207112E-6
medulloblastoma, large-cell 6234 3.92074255576437E-5
intraductal papillary-mucinous neoplasm (IPMN) 3289 1.00809328375351E-4
intraductal papillary-mucinous adenoma (IPMA) 2956 2.20760948410979E-4
osteosarcoma 7933 3.56332115542402E-4
pancreatic ductal adenocarcinoma liver metastasis 1795 0.0052184139394774
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.020600114110707
Disease Target Count Z-score Confidence
Cervical dystonia 9 5.544 2.8

Expression

Synonym

Accession Q9H305 A8K7M1 B4DFU1 B4DY75 D3DUD6 Q96ID8 Q9H0Q4 Q9P112
Symbols I1
CDIP
LITAFL
C16orf5

Gene

PANTHER Protein Class (1)

  Ortholog (8)

Gene RIF (3)

PMID Text
22549949 CDIP expression correlates with sensitivity of cancer cells with TNFalpha, and CDIP seems to be a regulator of the p53-mediated death versus survival response of cells to TNFalpha.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
17599062 These findings support a novel p53 --> CDIP --> TNF-alpha apoptotic pathway that directs apoptosis after exposure of cells to genotoxic stress.

AA Sequence

MSSEPPPPYPGGPTAPLLEEKSGAPPTPGRSSPAVMQPPPGMPLPPADIGPPPYEPPGHPMPQPGFIPPH      1 - 70
MSADGTYMPPGFYPPPGPHPPMGYYPPGPYTPGPYPGPGGHTATVLVPSGAATTVTVLQGEIFEGAPVQT     71 - 140
VCPHCQQAITTKISYEIGLMNFVLGFFCCFMGCDLGCCLIPCLINDFKDVTHTCPSCKAYIYTYKRLC      141 - 208
//

Text Mined References (14)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
22549949 2012 Expression of the p53 target CDIP correlates with sensitivity to TNF?-induced apoptosis in cancer cells.
21516116 2011 Next-generation sequencing to generate interactome datasets.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
17599062 2007 CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner.
16751776 2006 A germline-specific class of small RNAs binds mammalian Piwi proteins.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15616553 2004 The sequence and analysis of duplication-rich human chromosome 16.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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