Property Summary

NCBI Gene PubMed Count 13
PubMed Score 0.53
PubTator Score 0.86

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
lung carcinoma 2844 2.58166751407624E-21
juvenile dermatomyositis 1189 5.20093192240576E-11
acute quadriplegic myopathy 1157 3.20116483335878E-6
tuberculosis and treatment for 6 months 686 1.71455251333317E-4
intraductal papillary-mucinous neoplasm (IPMN) 3289 7.46481936733056E-4
aldosterone-producing adenoma 664 0.00899922196691366
ovarian cancer 8492 0.0121334950649526
primary pancreatic ductal adenocarcinoma 1271 0.0320657938453575
Disease Target Count Z-score Confidence
pancreatic cancer 2300 0.0 1.0

Expression

Synonym

Accession Q8NC42 Q53S14 Q8N5I8 Q8NBY5 Q8WUU3
Symbols DNAPTP2

Gene

  Ortholog (11)

Species Source
Chimp OMA EggNOG
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Pig OMA EggNOG
Opossum OMA EggNOG Inparanoid
Platypus EggNOG Inparanoid
Chicken OMA Inparanoid
Anole lizard OMA Inparanoid
Xenopus OMA Inparanoid

 GWAS Trait (1)

Gene RIF (1)

PMID Text
22628551 Data show that RNF149 (RING finger protein 149) interacts with wild-type BRAF.

AA Sequence

MAWRRREASVGARGVLALALLALALCVPGARGRALEWFSAVVNIEYVDPQTNLTVWSVSESGRFGDSSPK      1 - 70
EGAHGLVGVPWAPGGDLEGCAPDTRFFVPEPGGRGAAPWVALVARGGCTFKDKVLVAARRNASAVVLYNE     71 - 140
ERYGNITLPMSHAGTGNIVVIMISYPKGREILELVQKGIPVTMTIGVGTRHVQEFISGQSVVFVAIAFIT    141 - 210
MMIISLAWLIFYYIQRFLYTGSQIGSQSHRKETKKVIGQLLLHTVKHGEKGIDVDAENCAVCIENFKVKD    211 - 280
IIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGEPGDVQEMPAPESPPGRDPAANLSLALPD    281 - 350
DDGSDDSSPPSASPAESEPQCDPSFKGDAGENTALLEAGRSDSRHGGPIS                        351 - 400
//

Text Mined References (15)

PMID Year Title
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
22628551 2012 Ring finger protein 149 is an E3 ubiquitin ligase active on wild-type v-Raf murine sarcoma viral oncogene homolog B1 (BRAF).
20686608 2010 Genome-wide association study of pancreatic cancer in Japanese population.
19946888 2010 Defining the membrane proteome of NK cells.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16959974 2006 The consensus coding sequences of human breast and colorectal cancers.
16381901 2006 The LIFEdb database in 2006.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
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