Property Summary

NCBI Gene PubMed Count 7
Grant Count 9
R01 Count 9
Funding $1,725,561
PubMed Score 9.09
PubTator Score 6.01

Knowledge Summary

Patent (1,278)

TINX Plot

  Disease Relevance (1)

Disease Z-score Confidence
posterior fossa group B ependymoma 1,530

Expression

  Differential Expression (1)

Disease log2 FC p
posterior fossa group B ependymoma 1.800 0.000

Synonym

Accession Q8IV77
Symbols CNG4
CNG5
CNCA2
CNG-4
CNGB2
OCNC2
OCNCb
OCNCBETA

Gene

  TechDev Info (1)

Jing-Ruey Yeh gRNA validated for zebrafish model

AA Sequence

MSQDTKVKTTESSPPAPSKARKLLPVLDPSGDYYYWWLNTMVFPVMYNLIILVCRACFPDLQHGYLVAWL      1 - 70
VLDYTSDLLYLLDMVVRFHTGFLEQGILVVDKGRISSRYVRTWSFFLDLASLMPTDVVYVRLGPHTPTLR     71 - 140
LNRFLRAPRLFEAFDRTETRTAYPNAFRIAKLMLYIFVVIHWNSCLYFALSRYLGFGRDAWVYPDPAQPG    141 - 210
FERLRRQYLYSFYFSTLILTTVGDTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFY    211 - 280
PDHALVKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEVAILQHLPERLRAEVAVSVHLSTLSRVQIFQ    281 - 350
NCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREGQLAVVADDGITQYAVLGAGLYFGEISIIN    351 - 420
IKGNMSGNRRTANIKSLGYSDLFCLSKEDLREVLSEYPQAQTIMEEKGREILLKMNKLDVNAEAAEIALQ    421 - 490
EATESRLRGLDQQLDDLQTKFARLLAELESSALKIAYRIERLEWQTREWPMPEDLAEADDEGEPEEGTSK    491 - 560
DEEGRASQEGPPGPE                                                           561 - 575
//

Text Mined References (11)

PMID Year Title
17032767 2006 Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels.
16554811 2006 Human chromosome 11 DNA sequence and analysis including novel gene identification.
16382102 2005 International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15195096 2004 Calmodulin permanently associates with rat olfactory CNG channels under native conditions.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12649326 2003 Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11764791 2001 Nomenclature for ion channel subunits.
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