| Tbio | P2Y purinoceptor 8 |
Probable receptor for purines coupled to G-proteins.
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | 49 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Precursor Cell Lymphoblastic Leukemia Lymphoma | 43 |
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6694 | 2.9e-59 |
| periodontitis | 293 | 5.9e-24 |
| osteosarcoma | 7950 | 4.5e-09 |
| ulcerative colitis | 1819 | 1.5e-04 |
| interstitial cystitis | 2312 | 1.5e-03 |
| primary Sjogren syndrome | 735 | 1.6e-03 |
| ductal carcinoma in situ | 1745 | 3.1e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| acute lymphocytic leukemia | 33 | 4.459 | 2.2 |
| Down syndrome | 499 | 4.199 | 2.1 |
| interleukin-7 receptor alpha deficiency | 18 | 3.129 | 1.6 |
| Disease | log2 FC | p |
|---|---|---|
| ductal carcinoma in situ | 1.100 | 3.1e-02 |
| interstitial cystitis | 2.000 | 1.5e-03 |
| osteosarcoma | -4.794 | 4.5e-09 |
| periodontitis | 1.300 | 5.9e-24 |
| primary Sjogren syndrome | 1.700 | 1.6e-03 |
| psoriasis | 1.500 | 2.9e-59 |
| ulcerative colitis | 2.000 | 1.5e-04 |
MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDL 1 - 70 MLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYA 71 - 140 VAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITV 141 - 210 ACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLC 211 - 280 LSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRP 281 - 350 GLQRQESVF 351 - 359 //
