Property Summary

NCBI Gene PubMed Count 8
PubMed Score 1.70
PubTator Score 36.17

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (4)

Disease log2 FC p
psoriasis -1.200 0.000
osteosarcoma -1.865 0.000
tuberculosis and treatment for 6 months -1.100 0.001
aldosterone-producing adenoma -1.096 0.018

Synonym

Accession Q7L592 Q7Z399 Q9P1G3
Symbols MidA
C2orf56
PRO1853

Gene

Gene RIF (4)

PMID Text
24838397 NDUFAF7 functions to methylate NDUFS2 after it assembles into a complex I, stabilizing an early intermediate in the assembly pathway, and that this function is essential for normal vertebrate development.
24089531 NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I.
20877624 Observational study of gene-disease association. (HuGE Navigator)
20406883 a role for MidA in complex I assembly or stability

AA Sequence

MSVLLRSGLGPLCAVARAAIPFIWRGKYFSSGNEPAENPVTPMLRHLMYKIKSTGPITVAEYMKEVLTNP      1 - 70
AKGYYVYRDMLGEKGDFITSPEISQIFGELLGIWFISEWMATGKSTAFQLVELGPGRGTLVGDILRVFTQ     71 - 140
LGSVLKNCDISVHLVEVSQKLSEIQALTLTKEKVPLERNAGSPVYMKGVTKSGIPISWYRDLHDVPKGYS    141 - 210
FYLAHEFFDVLPVHKFQKTPQGWREVFVDIDPQVSDKLRFVLAPSATPAEAFIQHDETRDHVEVCPDAGV    211 - 280
IIEELSQRIALTGGAALVADYGHDGTKTDTFRGFCDHKLHDVLIAPGTADLTADVDFSYLRRMAQGKVAS    281 - 350
LGPIKQHTFLKNMGIDVRLKVLLDKSNEPSVRQQLLQGYDMLMNPKKMGERFNFFALLPHQRLQGGRYQR    351 - 420
NARQSKPFASVVAGFSELAWQ                                                     421 - 441
//

Text Mined References (14)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
24838397 2014 The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis.
24292274 2014 A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
24089531 2013 NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I.
22857522 2012 A three-dimensional topology of complex I inferred from evolutionary correlations.
22664934 2012 Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
21269460 2011 Initial characterization of the human central proteome.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
20406883 2010 MidA is a putative methyltransferase that is required for mitochondrial complex I function.
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