Property Summary

NCBI Gene PubMed Count 16
Grant Count 1
Funding $61,018.9
PubMed Score 3.70
PubTator Score 1.58

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (6)

Disease log2 FC p
osteosarcoma 2.824 0.001
group 4 medulloblastoma 3.600 0.000
cystic fibrosis -1.221 0.000
atypical teratoid/rhabdoid tumor 1.200 0.005
medulloblastoma, large-cell 2.200 0.000
primitive neuroectodermal tumor 1.900 0.007

Synonym

Accession Q6ZN04 Q4G0W1 Q8IVG2 Q9H0J0
Symbols RKHD3
MEX-3B
RNF195

Gene

 Grant Application (1)

Gene RIF (2)

PMID Text
22082156 Knockdown of mex-3 homolog B (C. elegans) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N
18779327 14-3-3 exerts combined effects on hMex-3B and acts as a major regulator of the sorting between distinct classes of RNA granules

AA Sequence

MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECV      1 - 70
PVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRAS     71 - 140
RNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGM    141 - 210
PENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKP    211 - 280
FSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASV    281 - 350
PSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPS    351 - 420
NANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDT    421 - 490
SGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTA    491 - 560
VTQAIRIFS                                                                 561 - 569
//

Text Mined References (18)

PMID Year Title
24677629 2014 A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
20531441 2010 CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19079261 2009 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
18779327 2008 Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17267406 2007 Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.
16381901 2006 The LIFEdb database in 2006.
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