| Tbio | Polypeptide N-acetylgalactosaminyltransferase 18 |
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung adenocarcinoma | 2716 | 6.1e-14 |
| non-small cell lung cancer | 2890 | 2.4e-10 |
| ovarian cancer | 8520 | 1.0e-08 |
| posterior fossa group A ependymoma | 468 | 2.5e-07 |
| group 4 medulloblastoma | 1855 | 2.1e-06 |
| Astrocytoma, Pilocytic | 3081 | 5.0e-06 |
| facioscapulohumeral dystrophy | 288 | 2.0e-05 |
| adult high grade glioma | 3801 | 2.6e-05 |
| Breast cancer | 3578 | 5.0e-05 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 1.6e-04 |
| primitive neuroectodermal tumor | 3035 | 2.6e-04 |
| atypical teratoid / rhabdoid tumor | 5112 | 2.1e-03 |
| astrocytic glioma | 2597 | 4.4e-03 |
| adrenocortical carcinoma | 1428 | 5.1e-03 |
| glioblastoma | 5792 | 8.5e-03 |
| active Crohn's disease | 922 | 1.6e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Rheumatoid arthritis | 1191 | 0.0 | 2.7 |
| Type 2 diabetes mellitus | 272 | 0.0 | 1.4 |
| Disease | log2 FC | p |
|---|---|---|
| active Crohn's disease | 1.008 | 1.6e-02 |
| adrenocortical carcinoma | 1.277 | 5.1e-03 |
| adult high grade glioma | -1.600 | 2.6e-05 |
| astrocytic glioma | -1.100 | 4.4e-03 |
| Astrocytoma, Pilocytic | -1.500 | 5.0e-06 |
| atypical teratoid / rhabdoid tumor | -1.100 | 2.1e-03 |
| Breast cancer | 1.200 | 5.0e-05 |
| facioscapulohumeral dystrophy | -1.800 | 2.0e-05 |
| glioblastoma | -1.100 | 8.5e-03 |
| group 4 medulloblastoma | -2.000 | 2.1e-06 |
| intraductal papillary-mucinous adenoma (... | -1.100 | 1.6e-04 |
| lung adenocarcinoma | -1.200 | 6.1e-14 |
| non-small cell lung cancer | -1.098 | 2.4e-10 |
| ovarian cancer | -2.100 | 1.0e-08 |
| posterior fossa group A ependymoma | -1.100 | 2.5e-07 |
| primitive neuroectodermal tumor | -1.600 | 2.6e-04 |
MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLE 1 - 70 NVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLR 71 - 140 PSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVD 141 - 210 KVNSQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSF 211 - 280 DNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEG 281 - 350 MEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMA 351 - 420 WNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTE 421 - 490 NVPIMYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQG 491 - 560 GPIQNRKSKRCLELQENSDLEFGFQLVLQKCSGQHWSITNVLRSLAS 561 - 607 //
