| Tdark | Polypeptide N-acetylgalactosaminyltransferase 18 |
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Comments
| Disease | log2 FC | p |
|---|---|---|
| astrocytic glioma | -1.100 | 0.004 |
| group 4 medulloblastoma | -2.000 | 0.000 |
| atypical teratoid / rhabdoid tumor | -1.100 | 0.002 |
| glioblastoma | -1.100 | 0.009 |
| primitive neuroectodermal tumor | -1.600 | 0.000 |
| adrenocortical carcinoma | 1.277 | 0.005 |
| non-small cell lung carcinoma | -1.100 | 0.000 |
| intraductal papillary-mucinous adenoma (... | -1.100 | 0.000 |
| active Crohn's disease | 1.008 | 0.016 |
| lung adenocarcinoma | -2.100 | 0.000 |
| adult high grade glioma | -1.600 | 0.000 |
| pilocytic astrocytoma | -1.500 | 0.000 |
| posterior fossa group B ependymoma | -1.200 | 0.000 |
| Breast cancer | 1.200 | 0.000 |
| ovarian cancer | -2.100 | 0.000 |
| facioscapulohumeral dystrophy | -1.800 | 0.000 |
| PMID | Text |
|---|---|
| 20379614 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 20080650 | Observational study of gene-disease association. (HuGE Navigator) |
| 19240061 | Observational study of gene-disease association. (HuGE Navigator) |
| 18976975 | Knockdown of UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 (GALNTL4) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells |
MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLE 1 - 70 NVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLR 71 - 140 PSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVD 141 - 210 KVNSQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSF 211 - 280 DNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEG 281 - 350 MEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMA 351 - 420 WNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTE 421 - 490 NVPIMYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQG 491 - 560 GPIQNRKSKRCLELQENSDLEFGFQLVLQKCSGQHWSITNVLRSLAS 561 - 607 //
| PMID | Year | Title |
|---|---|---|
| 22491018 | 2013 | Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. |
| 22238593 | 2012 | A genome-wide association search for type 2 diabetes genes in African Americans. |
| 22186971 | 2012 | UDP-N-acetyl-?-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. |
| 22171061 | 2012 | Characterization of ppGalNAc-T18, a member of the vertebrate-specific Y subfamily of UDP-N-acetyl-?-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases. |
| 20379614 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. |
| 19240061 | 2009 | Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
| More... |
