| Tdark | EEF1A lysine methyltransferase 2 |
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| osteosarcoma | 7950 | 5.9e-06 |
| atypical teratoid / rhabdoid tumor | 5112 | 2.0e-04 |
| adult high grade glioma | 3801 | 5.6e-04 |
| medulloblastoma, large-cell | 6241 | 7.4e-04 |
| glioblastoma | 5792 | 1.3e-03 |
| pituitary cancer | 1972 | 6.7e-03 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.300 | 5.6e-04 |
| atypical teratoid / rhabdoid tumor | -1.300 | 2.0e-04 |
| glioblastoma | -1.200 | 1.3e-03 |
| medulloblastoma, large-cell | -1.500 | 7.4e-04 |
| osteosarcoma | -2.306 | 5.9e-06 |
| pituitary cancer | 1.100 | 6.7e-03 |
MSSGADGGGGAAVAARSDKGSPGEDGFVPSALGTREHWDAVYERELQTFREYGDTGEIWFGEESMNRLIR 1 - 70 WMQKHKIPLDASVLDIGTGNGVFLVELAKFGFSNITGIDYSPSAIQLSGSIIEKEGLSNIKLKVEDFLNL 71 - 140 STQLSGFHICIDKGTFDAISLNPDNAIEKRKQYVKSLSRVLKVKGFFLITSCNWTKEELLNEFSEGWSTV 141 - 210 AGFWLTAALTSWAQAIFSTSASRVGGTTGTHHHAWIIFVFLAETRFCHVVQAGLELLGSSDSPTWPPKVL 211 - 280 GLYHARPSLAF 281 - 291 //
