Property Summary

NCBI Gene PubMed Count 11
PubMed Score 4.50
PubTator Score 7.66

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
group 3 medulloblastoma 2254 6.22008599375675E-7
medulloblastoma, large-cell 6234 1.28102830186459E-6
atypical teratoid / rhabdoid tumor 4369 2.0133478260714E-4
Pick disease 1893 3.42828806795911E-4
glioblastoma 5572 0.00148531481082097
primitive neuroectodermal tumor 3031 0.00158300670686243
lung cancer 4473 0.00303396686566579
psoriasis 6685 0.00547669338787566
osteosarcoma 7933 0.0108620965130652
non primary Sjogren syndrome sicca 840 0.0152401418184485
subependymal giant cell astrocytoma 2287 0.0430978209176746
active ulcerative colitis 477 0.0494432080406765
Disease Target Count Z-score Confidence
substance-related disorder 105 0.0 1.0

Expression

  Differential Expression (12)

Disease log2 FC p
psoriasis -1.100 0.005
osteosarcoma -1.167 0.011
group 3 medulloblastoma 2.400 0.000
atypical teratoid / rhabdoid tumor 1.300 0.000
glioblastoma 1.100 0.001
medulloblastoma, large-cell 3.000 0.000
primitive neuroectodermal tumor 1.700 0.002
lung cancer 1.300 0.003
active ulcerative colitis -1.242 0.049
non primary Sjogren syndrome sicca -1.600 0.015
subependymal giant cell astrocytoma 1.542 0.043
Pick disease 1.800 0.000

Synonym

Accession Q15973 B3KNP3 J3KSE1 Q15974 Q4VAJ7 Q5T2V4
Symbols ZK7
HZF16
HZF-16

Gene

  Ortholog (1)

Species Source
Chimp OMA EggNOG Inparanoid

Gene RIF (1)

PMID Text
22082156 Knockdown of zinc finger protein 124 (ZNF124) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N

AA Sequence

MSGHPGSWEMNSVAFEDVAVNFTQEEWALLDPSQKNLYRDVMQETFRNLASIGNKGEDQSIEDQYKNSSR      1 - 70
NLRHIISHSGNNPYGCEECGKKPCTCKQCQKTSLSVTRVHRDTVMHTGNGHYGCTICEKVFNIPSSFQIH     71 - 140
QRNHTGEKPYECMECGKALGFSRSLNRHKRIHTGEKRYECKQCGKAFSRSSHLRDHERTHTGEKPYECKH    141 - 210
CGKAFRYSNCLHYHERTHTGEKPYVCMECGKAFSCLSSLQGHIKAHAGEEPYPCKQCGKAFRYASSLQKH    211 - 280
EKTHIAQKPYVCNNCGKGFRCSSSLRDHERTHTGEKPYECQKCGKAFSRASTLWKHKKTHTGEKPYKCKK    281 - 350
M//

Text Mined References (11)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
21314694 2011 Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.
17431901 2007 Dandy-Walker complex in a boy with a 5 Mb deletion of region 1q44 due to a paternal t(1;20)(q44;q13.33).
16710414 2006 The DNA sequence and biological annotation of human chromosome 1.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12142086 2002 Expression of the Krüppel-type zinc finger gene, ZK7, in head and neck squamous cell carcinoma and normal mucosa.
10667597 2000 ZK7, a novel zinc finger gene, is induced by vascular endothelial growth factor and inhibits apoptotic death in hematopoietic cells.
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