| Tbio | Early activation antigen CD69 |
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]
Comments
| Disease | Target Count |
|---|---|
| Diabetes Mellitus, Insulin-Dependent | 48 |
| Spontaneous abortion | 113 |
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 5.9e-20 |
| non-small cell lung cancer | 2890 | 1.3e-19 |
| psoriasis | 6694 | 4.6e-08 |
| Astrocytoma, Pilocytic | 3081 | 8.5e-07 |
| lung cancer | 4740 | 1.7e-06 |
| glioblastoma | 5792 | 1.3e-05 |
| ulcerative colitis | 1819 | 1.7e-05 |
| lung adenocarcinoma | 2716 | 8.6e-05 |
| ependymoma | 4679 | 1.4e-04 |
| osteosarcoma | 7950 | 1.6e-04 |
| cutaneous lupus erythematosus | 1057 | 3.2e-04 |
| adult high grade glioma | 3801 | 4.7e-04 |
| Breast cancer | 3578 | 2.7e-03 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 2.8e-03 |
| acute myeloid leukemia | 783 | 3.2e-03 |
| hepatocellular carcinoma | 547 | 8.8e-03 |
| interstitial cystitis | 2312 | 2.1e-02 |
| non primary Sjogren syndrome sicca | 891 | 2.5e-02 |
| astrocytoma | 1146 | 2.9e-02 |
| invasive ductal carcinoma | 2951 | 3.2e-02 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 3.3e-02 |
| Waldenstrons macroglobulinemia | 765 | 3.4e-02 |
| aldosterone-producing adenoma | 665 | 4.1e-02 |
| interstitial lung disease | 298 | 4.2e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Type 1 diabetes mellitus | 109 | 0.0 | 3.0 |
| Disease | log2 FC | p |
|---|---|---|
| acute myeloid leukemia | 2.100 | 3.2e-03 |
| adult high grade glioma | 2.000 | 4.7e-04 |
| aldosterone-producing adenoma | -1.057 | 4.1e-02 |
| astrocytoma | 1.300 | 2.9e-02 |
| Astrocytoma, Pilocytic | 2.700 | 8.5e-07 |
| Breast cancer | -1.100 | 2.7e-03 |
| cutaneous lupus erythematosus | 3.700 | 3.2e-04 |
| ependymoma | 1.300 | 1.4e-04 |
| glioblastoma | 1.700 | 1.3e-05 |
| hepatocellular carcinoma | -1.100 | 8.8e-03 |
| interstitial cystitis | 1.300 | 2.1e-02 |
| interstitial lung disease | -2.500 | 4.2e-02 |
| intraductal papillary-mucinous carcinoma... | -2.400 | 2.8e-03 |
| intraductal papillary-mucinous neoplasm ... | -1.800 | 3.3e-02 |
| invasive ductal carcinoma | 1.600 | 3.2e-02 |
| lung adenocarcinoma | -1.100 | 8.6e-05 |
| lung cancer | -4.500 | 1.7e-06 |
| lung carcinoma | -3.200 | 5.9e-20 |
| non primary Sjogren syndrome sicca | -1.300 | 2.5e-02 |
| non-small cell lung cancer | -2.752 | 1.3e-19 |
| osteosarcoma | -4.007 | 1.6e-04 |
| psoriasis | -1.600 | 4.6e-08 |
| ulcerative colitis | 2.700 | 1.7e-05 |
| Waldenstrons macroglobulinemia | 2.133 | 3.4e-02 |
