Property Summary

NCBI Gene PubMed Count 6
PubMed Score 1.10
PubTator Score 1.00

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
oligodendroglioma 2849 5.33790048905555E-14
atypical teratoid / rhabdoid tumor 4369 2.20351918717876E-7
group 4 medulloblastoma 1875 3.33381962171464E-7
primitive neuroectodermal tumor 3031 1.71036001694224E-5
medulloblastoma, large-cell 6234 4.21109459307454E-5
psoriasis 6685 6.95000581738107E-5
lung cancer 4473 9.84145288873772E-5
ovarian cancer 8492 1.51756560871991E-4
tuberculosis and treatment for 3 months 327 4.3228649986021E-4
glioblastoma 5572 4.79045002926824E-4
osteosarcoma 7933 5.2345411933488E-4
pituitary cancer 1972 0.00119931639719198
adult high grade glioma 2148 0.00129484487515717
ependymoma 2514 0.00738962602948401
astrocytic glioma 2241 0.0194457056153548
colon cancer 1475 0.0332718829850312
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.0355197528168253

Expression

  Differential Expression (17)

Disease log2 FC p
astrocytic glioma 1.300 0.019
ependymoma 1.800 0.007
psoriasis -2.700 0.000
glioblastoma 1.500 0.000
oligodendroglioma 1.300 0.000
osteosarcoma -2.172 0.001
group 4 medulloblastoma 2.700 0.000
atypical teratoid / rhabdoid tumor 2.100 0.000
medulloblastoma, large-cell 1.900 0.000
primitive neuroectodermal tumor 1.800 0.000
tuberculosis and treatment for 3 months 1.200 0.000
intraductal papillary-mucinous carcinoma... 1.500 0.036
lung cancer -2.800 0.000
colon cancer 1.100 0.033
adult high grade glioma 1.400 0.001
ovarian cancer 1.200 0.000
pituitary cancer 1.100 0.001

Synonym

Accession Q03924 Q02313 Q7Z7Q7
Symbols HPF9
H-plk

Gene

  Ortholog (1)

Species Source
Chimp OMA EggNOG

Gene RIF (1)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence

MKRHEMVAKHLVMFYYFAQHLWPEQNIRDSFQKVTLRRYRKCGYENLQLRKGCKSVVECKQHKGDYSGLN      1 - 70
QCLKTTLSKIFQCNKYVEVFHKISNSNRHKMRHTENKHFKCKECRKTFCMLSHLTQHKRIQTRVNFYKCE     71 - 140
AYGRAFNWSSTLNKHKRIHTGEKPYKCKECGKAFNQTSHLIRHKRIHTEEKPYKCEECGKAFNQSSTLTT    141 - 210
HNIIHTGEIPYKCEKCVRAFNQASKLTEHKLIHTGEKRYECEECGKAFNRSSKLTEHKYIHTGEKLYKCE    211 - 280
ECGKAFNQSSTLTTHKRIHSGEKPYKCEECGKAFKQFSNLTDHKKIHTGEKPYKCEECGKAFNQLSNLTR    281 - 350
HKVIHTGEKPYKCGECGKAFNQSSALNTHKIIHTGENPHKCRESGKVFHLSSKLSTCKKIHTGEKLYKCE    351 - 420
ECGKAFNRSSTLIGHKRIHTGEKPYKCEECGKAFNQSSTLTTHKIIHTEEKQYKCDECGKAST           421 - 483
//

Text Mined References (7)

PMID Year Title
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
12853948 2003 The DNA sequence of human chromosome 7.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
2505992 The human genome contains hundreds of genes coding for finger proteins of the Krüppel type.
2115127 1990 Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Krüppel.
2023909 1991 The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.
1427907 1992 Localization of the human KRAB finger gene ZNF117 (HPF9) to chromosome 7q11.2.