Property Summary

NCBI Gene PubMed Count 11
PubMed Score 139.44
PubTator Score 59.14

Knowledge Summary


No data available


  Disease Sources (1)

Disease Target Count Z-score Confidence
Obesity 616 3.35 1.7


Accession P81277 PrRP
Symbols PRH


PANTHER Protein Class (2)

  Ortholog (6)

Species Source
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog OMA EggNOG Inparanoid
Horse OMA EggNOG
Cow OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid

Gene RIF (3)

23426574 Data indicate that formation of a primarily alpha-helical C-terminal region of prolactin releasing peptide (PrRP) is critical for receptor activation.
15891064 Review discusses the ancestral relationship between prolactin-releasing hormone and the C-terminal RF-motif amide precursor peptide (C-RF).
12126742 PrRP has a likely role in pheochromocytomas, based on its high expression in tumor tissue

AA Sequence

RLTCFPLEGGAMSSQDG                                                          71 - 87

Text Mined References (11)

PMID Year Title
23426574 2013 The activity of prolactin releasing peptide correlates with its helicity.
15891064 2005 The ancestry of the prolactin-releasing hormone precursor.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12126742 2002 Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of adrenocortical tumors, pheochromocytomas and neuroblastomas.
11523913 2001 Expression of prolactin-releasing peptide in human placenta and decidua.
11030716 2000 Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.
10599733 1999 Expression of prolactin-releasing peptide and its receptor messenger ribonucleic acid in normal human pituitary and pituitary adenomas.
10498338 1999 Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor.
10475064 1999 The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors.