Property Summary

NCBI Gene PubMed Count 56
Grant Count 16
Funding $669,831.81
PubMed Score 119.72
PubTator Score 99.06

Knowledge Summary

Patent

No data available

Expression

Gene RIF (42)

PMID Text
26320180 Dermal fibroblast CCL8 promotes melanoma metastasis.
26116899 HIV-1 Vpr upregulates the gene expression of CCL8 in human monocyte-derived dendritic cells
25253336 Authors show that the previously observed downregulation of hsa-miR-92a and upregulation of CCL8 during human cytomegalovirus latent infection of myeloid cells are intimately linked via the latency-associated expression of cytomegalovirus UL111A.
24742347 HIV-1 Vpr upregulates the gene expression of CCL8 in human monocyte-derived dendritic cells
24742347 HIV-1 Vpr upregulates the gene expression of CCL8 in human monocyte-derived dendritic cells
24196705 HIV-1 Vpr upregulates the gene expression of CCL8 in human monocyte-derived dendritic cells
23535064 HIV-1 Vpr upregulates the gene expression of CCL8 in human monocyte-derived dendritic cells
23418602 Results indicate that the induction of MCP-2/CCL8 by mycobacteria is dependent on the activation of TLR2/PI3K/Akt signaling pathway.
23383108 HIV-1 Vpr upregulates the gene expression of CCL8 in human monocyte-derived dendritic cells
22987449 JAK2 and STAT3 activation is not essential for CCL3, CCL5 or CCL8 induced chemotaxis.
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AA Sequence

MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCPKEAVIFKTKR      1 - 70
GKEVCADPKERWVRDSMKHLDQIFQNLKP                                              71 - 99
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Text Mined References (56)

PMID Year Title
26320180 2015 The importance of microenvironment: the role of CCL8 in metastasis formation of melanoma.
25253336 2014 Latency-associated viral interleukin-10 (IL-10) encoded by human cytomegalovirus modulates cellular IL-10 and CCL8 Secretion during latent infection through changes in the cellular microRNA hsa-miR-92a.
23418602 2013 Induction of CCL8/MCP-2 by mycobacteria through the activation of TLR2/PI3K/Akt signaling pathway.
22987449 2013 Janus kinase 2 and signal transducer and activator of transcription 3 activation is not essential for CCL3-, CCL5- or CCL8-induced chemotaxis.
22412388 2012 A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
21945122 2011 Macrophage colony stimulating factor and monocyte chemoattractant protein 2 are elevated in intrinsic asthmatics.
21514686 2011 Polymorphisms of key chemokine genes and survival of non-small cell lung cancer in Chinese.
21220697 2011 Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium.
20503287 2010 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
20438785 2010 Polymorphisms in innate immunity genes and risk of childhood leukemia.
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