Property Summary

NCBI Gene PubMed Count 9
PubMed Score 3.00
PubTator Score 1.84

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (12)

Disease log2 FC p
astrocytic glioma -1.300 0.014
atypical teratoid / rhabdoid tumor -1.300 0.000
glioblastoma -1.200 0.000
medulloblastoma, large-cell -1.900 0.000
primary pancreatic ductal adenocarcinoma 1.337 0.004
lung cancer -1.100 0.000
Breast cancer 2.100 0.049
adult high grade glioma -1.400 0.000
spina bifida -1.466 0.039
ovarian cancer -2.000 0.000
pancreatic cancer 1.200 0.018
dermatomyositis 1.300 0.000

Gene RIF (3)

PMID Text
23382248 results indicate that SCN-iPS cells provide a useful disease model for SCN, and the activation of the Wnt3a/beta-catenin pathway may offer a novel therapy for SCN with ELANE mutation
20580816 YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.
20508983 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNLQYSEVQDRVMLTGRHMVRD      1 - 70
VSCKNCNSKLGWIYEFATEDSQRYKEGRVILERALVRESEGFEEHVPSDNS                        71 - 121
//

Text Mined References (10)

PMID Year Title
23382248 2013 Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia.
21269460 2011 Initial characterization of the human central proteome.
20580816 2010 YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.
20508983 2011 Centrosome-related genes, genetic variation, and risk of breast cancer.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
15556292 2004 Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11240639 2001 The Drosophila gene Yippee reveals a novel family of putative zinc binding proteins highly conserved among eukaryotes.
10810093 2000 Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.