You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MNX1
Motor neuron and pancreas homeobox protein 1

Protein Summary
Description
Putative transcription factor involved in pancreas development and function. This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000252971
  • ENSP00000252971
  • ENSG00000130675
  • ENST00000543409
  • ENSP00000438552

Symbol
  • HLXB9
  • HB9
  • HLXB9
  • SCRA1
  • HOXHB9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor
0.84
virus perturbation
0.79
transcription factor binding site profile
0.71
PubMedID
0.65
small molecule perturbation
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 169.67   (req: < 5)
Gene RIFs: 40   (req: <= 3)
Antibodies: 172   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 169.67   (req: >= 5)
Gene RIFs: 40   (req: > 3)
Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0