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  6. Zinc finger protein 25

Tbio Zinc finger protein 25

May be involved in transcriptional regulation.

 Comments

Property Summary

NCBI Gene PubMed Count 11
PubMed Score 2.25
PubTator Score 1.88

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (13)

Disease Z-score Confidence
Multiple endocrine neoplasia type 2B 16 3.772 1.9
Amnestic disorder 37 3.463 1.7
Multiple endocrine neoplasia type 2A 22 3.425 1.7
Hearing Loss, Partial 25
Pick disease 1,893
adult high grade glioma 2,148
atypical teratoid / rhabdoid tumor 4,369
glioblastoma 5,572
hearing impairment 40
lung carcinoma 2,844
medulloblastoma, large-cell 6,234
ovarian cancer 8,484
posterior fossa group B ependymoma 1,530

Expression

  Differential Expression (8)

Disease log2 FC p
glioblastoma -1.600 0.000
posterior fossa group B ependymoma -1.300 0.000
atypical teratoid / rhabdoid tumor -1.800 0.000
medulloblastoma, large-cell -2.200 0.001
adult high grade glioma -1.500 0.000
lung carcinoma 1.300 0.000
Pick disease -1.100 0.020
ovarian cancer -1.200 0.000

Synonym

Accession P17030 A9Z1X5 Q8IYE3 Q8NDD6 Q96MU2
Symbols Zfp9
KOX19

Gene

ZNF25

PANTHER Protein Class (3)

 GO Function (2)

 GO Component (1)

 GO Process (2)

 Compartment GO Term (10)

Pathway (3)

 UniProt Keyword (12)

See all...

Gene RIF (1)

PMID Text
16385451 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence 

MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKLKQGKEPWILE      1 - 70
VEFPHRGFPEDLWSIHDLEARYQESQAGNSRNGELTKHQKTHTTEKACECKECGKFFCQKSALIVHQHTH     71 - 140
SKGKSYDCDKCGKSFSKNEDLIRHQKIHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKS    141 - 210
FYQKPHLTEHQKTHTGEKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMH    211 - 280
TGEKPYKCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKT    281 - 350
FYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQKSHFIIHQRKH    351 - 420
TGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK                                      421 - 456
//

Text Mined References (14)

PMID Year Title
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16959974 2006 The consensus coding sequences of human breast and colorectal cancers.
16385451 2006 A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15342556 2004 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
15164054 2004 The DNA sequence and comparative analysis of human chromosome 10.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12566394 2003 Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
More...