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Tbio
GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

Protein Summary
Description
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253778
  • ENSP00000253778
  • ENSG00000131459

Symbol
  • GFAT
  • GFAT2
  • GFAT 2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.99
gene perturbation
0.98
PubMedID
0.83
transcription factor perturbation
0.8
protein domain
0.73


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 124.66   (req: < 5)
Gene RIFs: 15   (req: <= 3)
Antibodies: 182   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 124.66   (req: >= 5)
Gene RIFs: 15   (req: > 3)
Antibodies: 182   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0