Property Summary

NCBI Gene PubMed Count 9
PubMed Score 0.55
PubTator Score 0.78

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
ovarian cancer 8492 5.084887342186E-15
astrocytoma 1493 9.9344728045701E-15
posterior fossa group A ependymoma 1511 1.18049781008436E-12
lung adenocarcinoma 2714 7.50177383320139E-10
interstitial cystitis 2299 1.4654785933202E-5
lung carcinoma 2844 2.32043725222135E-5
tuberculosis 1563 6.58969844693637E-5
lung cancer 4473 2.74654375275743E-4
atypical teratoid / rhabdoid tumor 4369 4.45421702893845E-4
group 4 medulloblastoma 1875 6.77372973037119E-4
medulloblastoma, large-cell 6234 8.38398768364849E-4
cystic fibrosis 1670 0.00142230005037135
pituitary cancer 1972 0.0015118937790585
glioblastoma 5572 0.00166625075020641
oligodendroglioma 2849 0.00566386754462068
adult high grade glioma 2148 0.0057045640289543
osteosarcoma 7933 0.00749244326200621
Breast cancer 3099 0.0241902584880038
Pick disease 1893 0.0321629654689101
Disease Target Count Z-score Confidence
Parathyroid carcinoma 5 3.391 1.7

Expression

  Differential Expression (19)

Disease log2 FC p
astrocytoma -1.500 0.000
posterior fossa group A ependymoma -3.500 0.000
oligodendroglioma -1.800 0.006
glioblastoma -3.200 0.002
osteosarcoma -1.278 0.007
group 4 medulloblastoma -3.000 0.001
cystic fibrosis -1.620 0.001
atypical teratoid / rhabdoid tumor -3.200 0.000
medulloblastoma, large-cell -3.700 0.001
tuberculosis -1.400 0.000
lung cancer 2.200 0.000
interstitial cystitis -2.200 0.000
lung adenocarcinoma -1.100 0.000
adult high grade glioma -2.400 0.006
Breast cancer 1.600 0.024
lung carcinoma 1.200 0.000
Pick disease -1.200 0.032
ovarian cancer -2.300 0.000
pituitary cancer 1.200 0.002

Synonym

Accession O43825 B2RAB1 Q9BZQ9 Beta-1,3-GalTase 2
Symbols GLCT2
BETA3GALT2
beta3Gal-T2

Gene

PANTHER Protein Class (2)

  Ortholog (10)

Gene RIF (6)

PMID Text
18565761 Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus
2829950 Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus
2649653 Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus
2542563 Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus
2541446 Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus
2187500 Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus

AA Sequence

MLQWRRRHCCFAKMTWNAKRSLFRTHLIGVLSLVFLFAMFLFFNHHDWLPGRAGFKENPVTYTFRGFRST      1 - 70
KSETNHSSLRNIWKETVPQTLRPQTATNSNNTDLSPQGVTGLENTLSANGSIYNEKGTGHPNSYHFKYII     71 - 140
NEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNESLAPGIQITRIFLLGLSIKLNGYLQRAILEESR    141 - 210
QYHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPHIPYVMKTDSDMFVNTEYLINKLLKPDLPPRHNYFTG    211 - 280
YLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAK    281 - 350
LRIDPVPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRK    351 - 420
LH                                                                        421 - 422
//

Text Mined References (10)

PMID Year Title
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16710414 2006 The DNA sequence and biological annotation of human chromosome 1.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11318611 2001 Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus.
10580128 1999 Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.
9582303 1998 A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family.
9417100 1998 Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase catalyzing the formation of type 1 chains.