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Tdark NACHT and WD repeat domain-containing protein 2


 Comments

Property Summary

NCBI Gene PubMed Count 3
PubMed Score 6.31
PubTator Score 0.33

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.9

Expression

  Differential Expression (14)

Disease log2 FC p
adult high grade glioma -4.300 1.8e-04
astrocytic glioma -3.200 6.5e-04
Astrocytoma, Pilocytic -4.100 7.5e-07
atypical teratoid / rhabdoid tumor -4.800 1.2e-09
cystic fibrosis 1.100 4.0e-04
ependymoma -3.500 5.5e-04
glioblastoma -4.100 4.3e-10
medulloblastoma -3.200 1.9e-02
medulloblastoma, large-cell -4.700 5.9e-04
oligodendroglioma -3.200 1.2e-03
primitive neuroectodermal tumor -4.400 1.8e-04
psoriasis 3.200 1.2e-156
subependymal giant cell astrocytoma -1.838 1.2e-02
ulcerative colitis -1.600 9.9e-05

Synonym

Accession Q9ULI1 A8MRU1
Symbols KIAA1239

Gene

NWD2

  Ortholog (12)

Species Source Disease
OMA EggNOG
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG
OMA EggNOG
OMA EggNOG
OMA EggNOG
OMA EggNOG
OMA EggNOG
OMA EggNOG
OMA EggNOG

 UniProt Keyword (6)

 Compartment GO Term (1)

 HCA RNA Cell Line (16)

See all...

Gene RIF (1)

AA Sequence 

MWPAGAGTKLPCPRDSALRRAAFSGNLTALPSHLVPAGRSVRVFISANPEDTGAERQALRENVYPKLREF      1 - 70
CRENYGLEFQVIDLYWGVEEDEWDSPELQKTRMKLLENCLKTSAGPCFVGLLGEKYGNIRIPGEVEASEF     71 - 140
EMILDAAIEAKLETKLLEEWYCRDENSVPAAYYLRPKSEMLRSNRNAMQPSTNAENEKTWQEISDEIKKI    141 - 210
FKAAVKLLHEKGKMKHSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMD    211 - 280
ITGTEPRIIRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYIEGLGKQFYEDM    281 - 350
IDIIQATIQQNFDTETDTLYDEILQHSSLCKTYASFYEYKCESLNIVHNYILPSKAGHINPLIIYGGPCT    351 - 420
GKTLLLAEVAKKAYGWLHEDTGPESDPVVIVRFLGTTDMSSDLRTLLLSVCEQLAVNYRCLVQSYPKKIH    421 - 490
DLCDLFINLLNESSLQRPLVIIFDALEQLSENDDARKLWWLPAHLPRFVRIVLSTLPNKHGILQKLRCLI    491 - 560
HEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNALSKCTLPMFVNLTFREVRHWRSHKDVD    561 - 630
ESSLSVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMSELKENTRPSNP    631 - 700
LRVPYLYIARLKEGLSGYLIERHVKNVTLLVWANRHLQLIAQKLYLQDDNDLREMHTILADYFLGVWSGG    701 - 770
RRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIFFVNHRKMSELLYH    771 - 840
LTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLSDIELAYNYSQEKELKFLANTLRSIKNKVTAFPGSL    841 - 910
SAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSHLHVTEILPTCNPS    911 - 980
TVLTALENGSISTWDVETRQLLRQITTAQSVILGMKLTSDEKYLVVATTNNTLLIYDNVNSCLLSEVEIK    981 - 1050
GTKHGSSATYINGFTLSANHALAWLEASKDVTVIDLLYGWPLYQFHCWYEVTCVQCSLDGLYAFCGQYLN   1051 - 1120
TTTIFHLGSGEKLCTVTSEFSGGFVKFLLILDTAQEMVMVDSEGSLSVWNTEDISSPQLTDDFDCRREDS   1121 - 1190
EVVSIELSEDQSAVLICKALSIELLDTGLWKVAEKFRAKHNERFISAVLSKNGDCIIATMENTSAVFFWR   1191 - 1260
RDTGQCMASLQEISGSIVKLVKSSHHNMLLSLSTSGVLSIWDIDIITAMSNIDKTGKPIQSLLLPARGEI   1261 - 1330
IYSLDGSDCVHKWNFSSGFIEAVFKHEGIVEHCVLTSTGDIMVTSDDKSSQYVWHTSSGENLFRINGQRI   1331 - 1400
SQLLITHNDQFVVSLCEENASRVWRLATGHRVCNILTTLQNAFITSANTFVVGMTKSKVLAVSLWTGSIT   1401 - 1470
KKFCCEDGTTIVNFKLIPDCPDIIVFITSAETVNIWSLTDEVICRRVQLPNNFLKNLEDFEISPNGKLGI   1471 - 1540
IARGDENINVLDLYSGKLRVVHASGIIWRQRLSRDGRYLVYICFRNGEEEDENGAIFSLIVMRLADGKNI   1541 - 1610
GACSLYKTPTFLALSQRHLNIIVGFDDGSIGIYTVVDRVDAALKIKIATSNSRQIFNNATHTSRPKCNSY   1611 - 1680
CFKISVDCLWRESTEVFARDSPITVSDSTESNEATPSKKHNSCYERVCSALEARGHSYAPDN           1681 - 1742
//

Text Mined References (5)

PMID Year Title