| Tclin | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Comments
| Disease | Target Count |
|---|---|
| Diabetes mellitus type 2 | 69 |
| Treatment Refractory Type 2 Diabetes Mellitus | 53 |
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 1.1e-05 |
| pancreatic ductal adenocarcinoma liver metastasis | 1962 | 6.9e-03 |
| non primary Sjogren syndrome sicca | 891 | 3.1e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Mitochondrial complex I deficiency | 46 | 0.0 | 5.0 |
| Disease | log2 FC | p |
|---|---|---|
| non primary Sjogren syndrome sicca | 1.400 | 3.1e-02 |
| ovarian cancer | 2.000 | 1.1e-05 |
| pancreatic ductal adenocarcinoma liver m... | -1.915 | 6.9e-03 |
