Property Summary

NCBI Gene PubMed Count 10
PubMed Score 13.62
PubTator Score 2.00

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (33)

Disease log2 FC p
astrocytic glioma -2.600 4.1e-02
ependymoma -2.400 4.4e-08
glioblastoma -1.100 1.9e-02
sonic hedgehog group medulloblastoma -4.800 3.4e-09
atypical teratoid / rhabdoid tumor -4.500 5.6e-06
medulloblastoma, large-cell -5.500 3.5e-08
primitive neuroectodermal tumor -2.800 9.9e-03
adrenocortical adenoma -1.497 3.6e-02
adrenocortical carcinoma -3.073 1.4e-06
pancreatic ductal adenocarcinoma liver m... -3.095 1.3e-02
non-small cell lung cancer -4.935 1.0e-25
intraductal papillary-mucinous adenoma (... -1.900 1.6e-02
intraductal papillary-mucinous carcinoma... -3.600 1.5e-02
intraductal papillary-mucinous neoplasm ... -4.200 6.3e-03
lung cancer -3.500 7.1e-06
colon cancer -2.100 1.9e-07
active Crohn's disease -2.383 3.1e-02
pancreatic cancer -2.900 8.4e-05
cystic fibrosis 1.700 1.9e-02
lung adenocarcinoma -3.300 1.0e-12
adult high grade glioma -1.400 7.3e-03
subependymal giant cell astrocytoma -2.059 8.5e-03
invasive ductal carcinoma -2.800 2.1e-04
Endometriosis -3.090 2.9e-02
Breast cancer -2.700 5.8e-41
lung carcinoma -1.500 5.2e-03
breast carcinoma -1.700 3.2e-25
spina bifida -2.406 4.8e-02
ductal carcinoma in situ -1.700 2.7e-03
ulcerative colitis -4.300 2.3e-08
ovarian cancer 1.700 3.3e-03
pituitary cancer -1.900 3.6e-04
head and neck cancer 2.200 4.9e-05

Gene RIF (3)

PMID Text
24782625 MT1M and MT1G promoter methylation may be used as serum biomarkers for noninvasive detection of hepatocellular carcinoma.
22971577 Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas.
12539042 Microarray analysis indicates HIV-1 Tat upregulates the interferon-responsive gene expression of many proteins, including Metallothionein, in immature dendritic cells, an effect that likely facilitates the expansion of HIV-1 infection

AA Sequence

MDPNCSCTTGVSCACTGSCTCKECKCTSCKKSCCSCCPVGCAKCAHGCVCKGTLENCSCCA               1 - 61
//

Text Mined References (10)

PMID Year Title
24782625 2014 MT1M and MT1G promoter methylation as biomarkers for hepatocellular carcinoma.
22971577 2012 Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas.
17244347 2007 Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12539042 2003 HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
10774930 2000 Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes.
10575295 1999 Metallothioneins in human kidneys and associated tumors.
8049263 1994 Characterisation of six additional human metallothionein genes.
2286373 1990 Human metallothionein genes: structure of the functional locus at 16q13.