Property Summary

NCBI Gene PubMed Count 20
PubMed Score 21.88
PubTator Score 14.58

Knowledge Summary


No data available


  Differential Expression (17)

Disease log2 FC p
progressive supranuclear palsy -1.600 4.5e-02
astrocytic glioma -3.200 4.0e-02
ependymoma -4.400 2.0e-20
glioblastoma -3.700 1.1e-05
oligodendroglioma -2.300 2.7e-07
sonic hedgehog group medulloblastoma -4.400 6.3e-06
atypical teratoid/rhabdoid tumor -4.600 5.3e-10
medulloblastoma, large-cell -4.100 1.5e-04
primitive neuroectodermal tumor -3.800 3.0e-04
active Crohn's disease -1.059 3.0e-02
active ulcerative colitis -1.219 2.4e-02
pediatric high grade glioma -4.100 5.5e-07
pilocytic astrocytoma -4.500 8.5e-09
non primary Sjogren syndrome sicca -1.100 2.0e-02
subependymal giant cell astrocytoma -6.082 1.9e-03
ovarian cancer 1.100 8.8e-10
Down syndrome 1.100 2.5e-02

Gene RIF (6)

26077951 rs1768208 is associated with corticobasal degeneration.
24994843 The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia.
23116876 Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk.
20877624 Observational study of gene-disease association. (HuGE Navigator)
17964117 MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse.
15009677 Decreased expression of a number of myelin-related genes, including myelin basic protein (MBP), proteolipid protein (PLP), and myelin-associated oligodendrocyte basic protein (MOBP) was noted in nucleus accumbens of cocaine abusers

AA Sequence


Text Mined References (21)

PMID Year Title
26871637 2016 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
26077951 2015 Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
25416956 2014 A proteome-scale map of the human interactome network.
24994843 2014 Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.
23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
23116876 2013 An exploratory study on STX6, MOBP, MAPT, and EIF2AK3 and late-onset Alzheimer's disease.
21685912 2011 Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
19734545 2009 A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
18839057 2008 Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17964117 2008 Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16641997 2006 The DNA sequence, annotation and analysis of human chromosome 3.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15009677 2004 Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
9749786 1998 Cytoskeletal and nuclear localization of myelin oligodendrocytic basic protein isoforms.
7989345 1994 Cloning and expression of myelin-associated oligodendrocytic basic protein. A novel basic protein constituting the central nervous system myelin.