| Tbio | Homeobox protein Mohawk |
May act as a morphogenetic regulator of cell adhesion.
The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jun 2011]
The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jun 2011]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| glioblastoma | 5792 | 2.2e-08 |
| Astrocytoma, Pilocytic | 3081 | 1.3e-05 |
| pituitary cancer | 1972 | 2.1e-05 |
| primitive neuroectodermal tumor | 3035 | 8.1e-05 |
| adult high grade glioma | 3801 | 1.9e-03 |
| ependymoma | 4679 | 4.5e-03 |
| group 3 medulloblastoma | 4104 | 8.0e-03 |
| medulloblastoma, large-cell | 6241 | 1.9e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| ulcerative colitis | 1819 | 0.0 | 1.1 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -2.000 | 1.9e-03 |
| Astrocytoma, Pilocytic | -2.200 | 1.3e-05 |
| ependymoma | 1.600 | 4.5e-03 |
| glioblastoma | -2.300 | 2.2e-08 |
| group 3 medulloblastoma | -2.100 | 8.0e-03 |
| medulloblastoma, large-cell | -2.200 | 1.9e-02 |
| pituitary cancer | -3.400 | 2.1e-05 |
| primitive neuroectodermal tumor | -2.700 | 8.1e-05 |
MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHRRTGARQNGGK 1 - 70 VRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWA 71 - 140 LRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRASE 141 - 210 DYVAPPKYKSSLLNRYLNDSLRHVMATNTTMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTD 211 - 280 TLENGSNKGESAANRKGPSKDDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQ 281 - 350 QF 351 - 352 //
