Metallo-beta-lactamase domain-containing protein 1

Property Summary

NCBI Gene PubMed Count	2
PubMed Score	1.17

PubTator Score	0.33

Knowledge Summary

Patent

No data available

TINX Plot

Disease (1)

JensenLab Experiment COSMIC

Disease	Target Count	Z-score	Confidence
Carcinoma	11493	0.0	0.5

Expression

Specificity
Differential

Brain - Cerebellar Hemisphere 18,015

Brain - Cerebellum 17,983

Brain - Frontal Cortex (BA9) 18,069

Ovary 17,971

Brain - Cortex 18,039

Pituitary 18,147

Uterus 17,618

Prostate 18,213

Testis 18,518

Vagina 17,834

Brain - Anterior cingulate cortex (BA24) 17,989

Thyroid 18,024

Brain - Nucleus accumbens (basal ganglia... 18,024

Esophagus - Muscularis 18,017

Colon - Sigmoid 18,089

Artery - Aorta 17,896

Brain - Hypothalamus 18,169

Esophagus - Gastroesophageal Junction 18,000

Brain - Hippocampus 18,011

Nerve - Tibial 18,007

Esophagus - Mucosa 18,076

Brain - Amygdala 18,006

Brain - Caudate (basal ganglia) 18,001

Stomach 17,879

Artery - Coronary 17,949

Artery - Tibial 17,631

Skin - Sun Exposed (Lower leg) 17,968

Adrenal Gland 18,071

Cells - Transformed fibroblasts 17,577

Minor Salivary Gland 18,005

Skin - Not Sun Exposed (Suprapubic) 18,081

Small Intestine - Terminal Ileum 17,954

Brain - Spinal cord (cervical c-1) 17,973

Cells - EBV-transformed lymphocytes 18,186

Breast - Mammary Tissue 18,103

Brain - Substantia nigra 17,981

Spleen 17,614

Brain - Putamen (basal ganglia) 17,863

Adipose - Subcutaneous 18,110

Adipose - Visceral (Omentum) 17,937

Heart - Atrial Appendage 17,896

Kidney - Cortex 17,329

Lung 18,057

Muscle - Skeletal 17,778

Liver 18,071

Colon - Transverse 17,825

Heart - Left Ventricle 18,006

Pancreas 18,123

Whole Blood 17,439

Adult Gallbladder 7,612

Adult Pancreas 9,168

Adult Prostate 8,952

Fetal Ovary 9,118

CD8 Cells 9,840

Gall bladder

Ovary

Pancreas

Prostate gland

BTO:0004410

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

Brain 7,346

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Synonym

Accession	A4D2B0 Q8N5X8
Symbols

Gene

MBLAC1

Ortholog (8)

Species	Source	Disease
Cow 15,320	Inparanoid OMA EggNOG
Horse 14,252	Inparanoid OMA EggNOG
Anole lizard 10,588	Inparanoid OMA EggNOG
Opossum 12,230	Inparanoid OMA EggNOG
Zebrafish 9,726	OMA EggNOG
Chimp 14,140	OMA EggNOG
Rat 15,117	Inparanoid OMA EggNOG
Mouse 16,570	Inparanoid OMA EggNOG

UniProt Keyword (7)

Complete proteome 20,231

Metal-binding 3,672

Polymorphism 12,194

Reference proteome 20,231

Zinc 2,356

3D-structure 6,226

Hydrolase 1,654

GO Function (2)

metal ion binding 2,256

hydrolase activity 80

Compartment GO Term (0)

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Protein-protein Interaction (2)

PDB (1)

...
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AA Sequence

MRTEPLCGASPLLVPGDPYSVVVLLQGYAEPEGVGDAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEA      1 - 70
ALEEAARGPILVDTGGPWAREALLGALAGQGVAPGDVTLVVGTHGHSDHIGNLGLFPGAALLVSHDFCLP     71 - 140
GGRYLPHGLGEGQPLRLGPGLEVWATPGHGGQRDVSVVVAGTALGTVVVAGDVFERDGDEDSWQALSEDP    141 - 210
AAQERSRKRVLVVADVVVPGHGPPFRVLREASQPETEGGGNSQQEPVVGDEEPALH                  211 - 266
//

Text Mined References (4)

Summary
Details

	PMID	Year	Title