| Tbio | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity).
Comments
| Disease | Target Count |
|---|---|
| Major Depressive Disorder | 301 |
| Unipolar Depression | 250 |
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 3.1e-39 |
| atypical teratoid/rhabdoid tumor | 357 | 4.9e-06 |
| osteosarcoma | 7950 | 1.4e-04 |
| group 3 medulloblastoma | 4104 | 1.8e-04 |
| glioblastoma | 5792 | 2.0e-04 |
| pediatric high grade glioma | 1064 | 2.7e-04 |
| psoriasis | 6694 | 5.1e-03 |
| subependymal giant cell astrocytoma | 2287 | 1.2e-02 |
| non primary Sjogren syndrome sicca | 891 | 1.4e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Acquired metabolic disease | 336 | 0.0 | 0.9 |
| Cardiovascular system disease | 246 | 0.0 | 0.7 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Melancholia | 10 | 3.737 | 1.9 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid/rhabdoid tumor | -1.500 | 4.9e-06 |
| glioblastoma | -1.300 | 2.0e-04 |
| group 3 medulloblastoma | -2.600 | 1.8e-04 |
| lung carcinoma | 1.600 | 3.1e-39 |
| non primary Sjogren syndrome sicca | 1.300 | 1.4e-02 |
| osteosarcoma | -1.914 | 1.4e-04 |
| pediatric high grade glioma | -1.300 | 2.7e-04 |
| psoriasis | -1.100 | 5.1e-03 |
| subependymal giant cell astrocytoma | -1.511 | 1.2e-02 |
MAPWGKRLAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQLQR 1 - 70 LGFDISEQEVTAPAPAACQILKEQGLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAGESFSYQNMNNAFQ 71 - 140 VLMELEKPVLISLGKGRYYKETSGLMLDVGPYMKALEYACGIKAEVVGKPSPEFFKSALQAIGVEAHQAV 141 - 210 MIGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEHHPEVKADGYVDNLAEAVDLLLQHADK 211 - 270 //
