Tdark | Keratin-associated protein 5-7 |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Comments
Disease | log2 FC | p |
---|---|---|
diabetes mellitus | 2.500 | 1.1e-03 |
psoriasis | -1.200 | 1.1e-04 |