Property Summary

NCBI Gene PubMed Count 12
PubMed Score 152.72
PubTator Score 7.19

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (27)

Disease log2 FC p
astrocytic glioma -3.000 1.2e-03
ependymoma -3.100 3.1e-03
oligodendroglioma -2.300 6.3e-03
glioblastoma -2.700 1.1e-05
osteosarcoma 2.120 1.4e-06
medulloblastoma -3.700 2.7e-07
cystic fibrosis 2.023 9.9e-06
atypical teratoid / rhabdoid tumor -2.200 3.1e-03
medulloblastoma, large-cell -4.100 1.1e-05
primitive neuroectodermal tumor -2.500 4.3e-03
acute quadriplegic myopathy 1.567 5.7e-06
Atopic dermatitis 1.200 9.6e-05
adrenocortical carcinoma -1.547 2.0e-03
primary pancreatic ductal adenocarcinoma 1.472 7.2e-03
non-small cell lung cancer 1.107 2.3e-15
intraductal papillary-mucinous adenoma (... 2.300 2.3e-06
intraductal papillary-mucinous carcinoma... 2.300 9.1e-05
intraductal papillary-mucinous neoplasm ... 1.800 2.2e-03
interstitial cystitis -1.400 2.0e-04
adult high grade glioma -2.300 1.1e-03
aldosterone-producing adenoma -1.057 3.2e-03
lung carcinoma -1.200 1.1e-06
Breast cancer -1.600 2.7e-21
invasive ductal carcinoma 1.200 2.2e-02
ovarian cancer 2.700 6.2e-05
pituitary cancer -1.600 1.7e-05
pancreatic cancer 1.500 1.1e-02

Gene RIF (5)

PMID Text
23333304 HIV-1 Vif upregulates the expression of sickle tail protein homolog (SKT, KIAA1217) in Vif-expression T cells
22107760 SKT is involved in the etiology of intervertebral disc degeneration among young adults.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19338451 Using tag SNPs, we examined the association in two independent Japanese case-control populations and found a significant association of lumbar herniation with SKT rs16924573 in the allele frequency model
19338451 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)

AA Sequence

MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLG      1 - 70
GPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL     71 - 140
SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTI    141 - 210
RALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGD    211 - 280
MRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR    281 - 350
ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH    351 - 420
IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHY    421 - 490
NAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR    491 - 560
ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVP    561 - 630
PSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPV    631 - 700
QRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG    701 - 770
EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM    771 - 840
EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNL    841 - 910
PHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD    911 - 980
HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPP    981 - 1050
PPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSS   1051 - 1120
KDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKS   1121 - 1190
DVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQ   1191 - 1260
ETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSV   1261 - 1330
HDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEV   1331 - 1400
HDIVSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEE   1401 - 1470
LERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNR   1471 - 1540
TELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEE   1541 - 1610
DGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTI   1611 - 1680
SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPV   1681 - 1750
PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSG   1751 - 1820
DSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPP   1821 - 1890
LSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS                    1891 - 1943
//

Text Mined References (20)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23563609 2013 Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22107760 2011 Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.
20585627 2010 Web-based, participant-driven studies yield novel genetic associations for common traits.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
20125193 2010 Common genetic variation and performance on standardized cognitive tests.
19338451 2009 Association of the tag SNPs in the human SKT gene (KIAA1217) with lumbar disc herniation.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
15951569 2005 Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15164054 2004 The DNA sequence and comparative analysis of human chromosome 10.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12168954 2002 Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
10574462 1999 Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.