| Tdark | Actin-binding protein IPP |
May play a role in organizing the actin cytoskeleton.
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | 243 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| ependymoma | 4679 | 3.5e-15 |
| Astrocytoma, Pilocytic | 3081 | 1.3e-07 |
| osteosarcoma | 7950 | 4.7e-06 |
| atypical teratoid / rhabdoid tumor | 5112 | 6.0e-06 |
| pediatric high grade glioma | 1064 | 7.6e-06 |
| medulloblastoma, large-cell | 6241 | 1.3e-04 |
| group 3 medulloblastoma | 4104 | 1.6e-04 |
| glioblastoma | 5792 | 3.6e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 8.2e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Multiple Sclerosis | 540 | 0.0 | 0.9 |
| Disease | log2 FC | p |
|---|---|---|
| Astrocytoma, Pilocytic | 1.100 | 1.3e-07 |
| atypical teratoid / rhabdoid tumor | 1.600 | 6.0e-06 |
| ependymoma | 1.700 | 3.5e-15 |
| glioblastoma | 1.300 | 3.6e-04 |
| group 3 medulloblastoma | 1.300 | 1.6e-04 |
| intraductal papillary-mucinous carcinoma... | 1.100 | 8.2e-03 |
| medulloblastoma, large-cell | 1.300 | 1.3e-04 |
| osteosarcoma | 1.641 | 4.7e-06 |
| pediatric high grade glioma | 1.300 | 7.6e-06 |
MANEDCPKAADSPFSSDKHAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGM 1 - 70 KESSKDVVPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPLNCI 71 - 140 GIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEELSIEDEYQVFLAAMQWILK 141 - 210 DLGKRRKHVVEVLDPIRFPLLPPQRLLKYIEGVSDFNLRVALQTLLKEYCEVCKSPKENKFCSFLQTSKV 211 - 280 RPRKKARKYLYAVGGYTRLQGGRWSDSRALSCVERFDTFSQYWTTVSSLHQARSGLGVTVLGGMVYAIGG 281 - 350 EKDSMIFDCTECYDPVTKQWTTVASMNHPRCGLGVCVCYGAIYALGGWVGAEIGNTIERFDPDENKWEVV 351 - 420 GNMAVSRYYFGCCEMQGLIYVIGGISNEGIELRSFEVYDPLSKRWSPLPPMGTRRAYLGVAALNDCIYSV 421 - 490 GGWNETQDALHTVEKYSFEEEKWVEVASMKVPRAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYN 491 - 560 PHSDTWTEIGNMITSRCEGGVAVL 561 - 584 //
