Tbio Putative nuclease HARBI1

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Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

Property Summary

NCBI Gene PubMed Count	8
PubMed Score	0.83

PubTator Score	1.75

Knowledge Summary

Patent

No data available

Expression

Specificity
Differential

Testis 18,518

Cells - EBV-transformed lymphocytes 18,186

Pituitary 18,147

Skin - Sun Exposed (Lower leg) 17,968

Cells - Transformed fibroblasts 17,577

Skin - Not Sun Exposed (Suprapubic) 18,081

Brain - Spinal cord (cervical c-1) 17,973

Nerve - Tibial 18,007

Small Intestine - Terminal Ileum 17,954

Thyroid 18,024

Minor Salivary Gland 18,005

Spleen 17,614

Breast - Mammary Tissue 18,103

Prostate 18,213

Adipose - Subcutaneous 18,110

Adrenal Gland 18,071

Brain - Hypothalamus 18,169

Uterus 17,618

Brain - Substantia nigra 17,981

Brain - Frontal Cortex (BA9) 18,069

Colon - Sigmoid 18,089

Brain - Caudate (basal ganglia) 18,001

Brain - Nucleus accumbens (basal ganglia... 18,024

Brain - Cortex 18,039

Adipose - Visceral (Omentum) 17,937

Brain - Putamen (basal ganglia) 17,863

Esophagus - Mucosa 18,076

Esophagus - Muscularis 18,017

Artery - Coronary 17,949

Colon - Transverse 17,825

Artery - Tibial 17,631

Esophagus - Gastroesophageal Junction 18,000

Vagina 17,834

Brain - Hippocampus 18,011

Ovary 17,971

Artery - Aorta 17,896

Brain - Cerebellum 17,983

Stomach 17,879

Brain - Cerebellar Hemisphere 18,015

Brain - Amygdala 18,006

Brain - Anterior cingulate cortex (BA24) 17,989

Liver 18,071

Pancreas 18,123

Heart - Atrial Appendage 17,896

Muscle - Skeletal 17,778

Lung 18,057

Kidney - Cortex 17,329

Whole Blood 17,439

Heart - Left Ventricle 18,006

Colon

Ovary

Pancreas

Rectum

Testis

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

Pancreas 833

Testis 3,897

See source...

See source...

Synonym

Accession	Q96MB7 D3DQP9
Symbols	C11orf77

Gene

HARBI1

Ortholog (13)

Species	Source	Disease
Rat 15,117	Inparanoid OMA EggNOG
Dog 15,073	Inparanoid OMA EggNOG
Horse 14,252	Inparanoid OMA EggNOG
Cow 15,320	Inparanoid OMA EggNOG
Pig 10,168	Inparanoid OMA EggNOG
Opossum 12,230	Inparanoid OMA EggNOG
Platypus 5,703	OMA EggNOG
Chicken 7,827	Inparanoid OMA EggNOG
Anole lizard 10,588	Inparanoid OMA EggNOG
Xenopus 10,468	Inparanoid OMA EggNOG
Zebrafish 9,726	Inparanoid OMA
Chimp 14,140	OMA EggNOG
Mouse 16,570	Inparanoid OMA EggNOG

UniProt Keyword (7)

Complete proteome 20,231

Metal-binding 3,672

Nucleus 5,259

Reference proteome 20,231

Cytoplasm 4,952

Hydrolase 1,654

Nuclease 132

GO Function (2)

metal ion binding 2,256

nuclease activity 13

GO Component (4)

nucleus 5,097

cytosol 4,834

plasma membrane 4,414

microtubule organizing center 153

Compartment GO Term (24)

Cell 16,178

Cell part 16,177

Cell periphery 5,382

Cytoplasm 10,983

Cytoplasmic part 9,247

Cytoskeletal part 1,637

Cytoskeleton 2,108

Cytosol 6,686

Intracellular 14,109

Intracellular membrane-bounded organelle 10,341

Intracellular non-membrane-bounded organ... 3,975

Intracellular organelle 12,025

Intracellular organelle part 8,783

Intracellular part 13,972

Membrane 8,531

See all...

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Protein-protein Interaction (1)

Gene RIF (1)

AA Sequence

MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPE      1 - 70
TQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAG     71 - 140
MPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSS    141 - 210
QFEAGMHKDSWLLGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGA    211 - 280
LQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS     281 - 349
//

Text Mined References (8)

Summary
Details

	PMID	Year	Title